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Monomeric CRP Aggravates Myocardial Injury After Myocardial Infarction by Polarizing the Macrophage to Pro-Inflammatory Phenotype Through JNK Signaling Pathway
OBJECTIVE: A polarized macrophage response plays a critical role in the pathophysiological process of myocardial infarction (MI). Several studies have shown a pro-inflammatory role for monomeric C-reactive protein (mCRP) in cardiovascular disease. However, the mechanism of how mCRP regulates macroph...
Autores principales: | Zha, Zhimin, Cheng, Yujia, Cao, Lu, Qian, Yanxia, Liu, Xinjian, Guo, Yan, Wang, Junhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703048/ https://www.ncbi.nlm.nih.gov/pubmed/34984018 http://dx.doi.org/10.2147/JIR.S316816 |
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