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Gβγ mediates activation of Rho guanine nucleotide exchange factor ARHGEF17 that promotes metastatic lung cancer progression

Metastatic lung cancer is a major cause of death worldwide. Dissemination of cancer cells can be facilitated by various agonists within the tumor microenvironment, including by lysophosphatidic acid (LPA). We postulate that Rho guanine nucleotide exchange factors (RhoGEFs), which integrate signaling...

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Detalles Bibliográficos
Autores principales:	García-Jiménez, Irving, Cervantes-Villagrana, Rodolfo Daniel, del-Río-Robles, Jorge Eduardo, Castillo-Kauil, Alejandro, Beltrán-Navarro, Yarely Mabell, García-Román, Jonathan, Reyes-Cruz, Guadalupe, Vázquez-Prado, José
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703085/ https://www.ncbi.nlm.nih.gov/pubmed/34808208 http://dx.doi.org/10.1016/j.jbc.2021.101440

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