Deoxyribonucleic Acid 5-Hydroxymethylation in Cell-Free Deoxyribonucleic Acid, a Novel Cancer Biomarker in the Era of Precision Medicine

Aberrant methylation has been regarded as a hallmark of cancer. 5-hydroxymethylcytosine (5hmC) is recently identified as the ten-eleven translocase (ten-eleven translocase)-mediated oxidized form of 5-methylcytosine, which plays a substantial role in DNA demethylation. Cell-free DNA has been introdu...

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Detalles Bibliográficos
Autores principales: Xu, Ling, Zhou, Yixin, Chen, Lijie, Bissessur, Abdul Saad, Chen, Jida, Mao, Misha, Ju, Siwei, Chen, Lini, Chen, Cong, Li, Zhaoqin, Zhang, Xun, Chen, Fei, Cao, Feilin, Wang, Linbo, Wang, Qinchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703110/
https://www.ncbi.nlm.nih.gov/pubmed/34957093
http://dx.doi.org/10.3389/fcell.2021.744990

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