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Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology

Objective: The cerebellar functional laterality, with its right hemisphere predominantly involved in verbal performance and the left one engaged in visuospatial processes, has strong empirical support. However, the clinical observation and single research results show that the damage to the right ce...

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Autores principales: Starowicz-Filip, Anna, Prochwicz, Katarzyna, Kłosowska, Joanna, Chrobak, Adrian Andrzej, Myszka, Aneta, Bętkowska-Korpała, Barbara, Kwinta, Borys
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703197/
https://www.ncbi.nlm.nih.gov/pubmed/34955995
http://dx.doi.org/10.3389/fpsyg.2021.775308
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author Starowicz-Filip, Anna
Prochwicz, Katarzyna
Kłosowska, Joanna
Chrobak, Adrian Andrzej
Myszka, Aneta
Bętkowska-Korpała, Barbara
Kwinta, Borys
author_facet Starowicz-Filip, Anna
Prochwicz, Katarzyna
Kłosowska, Joanna
Chrobak, Adrian Andrzej
Myszka, Aneta
Bętkowska-Korpała, Barbara
Kwinta, Borys
author_sort Starowicz-Filip, Anna
collection PubMed
description Objective: The cerebellar functional laterality, with its right hemisphere predominantly involved in verbal performance and the left one engaged in visuospatial processes, has strong empirical support. However, the clinical observation and single research results show that the damage to the right cerebellar hemisphere may cause extralinguistic and more global cognitive decline. The aim of our research was to assess the pattern of cognitive functioning, depending on the cerebellar lesion side, with particular emphasis on the damage to the right cerebellar hemisphere. Method: The study sample consisted of 31 patients with focal cerebellar lesions and 31 controls, free of organic brain damage. The Addenbrooke’s Cognitive Examination ACE III and the Trail Making Test TMT were used to assess patients’ cognitive functioning. Results: Left-sided cerebellar lesion patients scored lower than controls in attention and visuospatial domain, but not in language, fluency, and memory functions. Participants with right-sided cerebellar lesion demonstrated a general deficit of cognitive functioning, with impairments not only in language and verbal fluency subscales but also in all ACE III domains, including memory, attention, and visuospatial functions. The TMT results proved that cerebellar damage is associated with executive function impairment, regardless of the lesion side. Conclusion: The cognitive profiles of patients with cerebellum lesions differ with regard to the lesion side. Left-sided cerebellar lesions are associated with selective visuospatial and attention impairments, whereas the right-sided ones may result in a more global cognitive decline, which is likely secondary to language deficiencies, associated with this lateral cerebellar injury.
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spelling pubmed-87031972021-12-25 Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology Starowicz-Filip, Anna Prochwicz, Katarzyna Kłosowska, Joanna Chrobak, Adrian Andrzej Myszka, Aneta Bętkowska-Korpała, Barbara Kwinta, Borys Front Psychol Psychology Objective: The cerebellar functional laterality, with its right hemisphere predominantly involved in verbal performance and the left one engaged in visuospatial processes, has strong empirical support. However, the clinical observation and single research results show that the damage to the right cerebellar hemisphere may cause extralinguistic and more global cognitive decline. The aim of our research was to assess the pattern of cognitive functioning, depending on the cerebellar lesion side, with particular emphasis on the damage to the right cerebellar hemisphere. Method: The study sample consisted of 31 patients with focal cerebellar lesions and 31 controls, free of organic brain damage. The Addenbrooke’s Cognitive Examination ACE III and the Trail Making Test TMT were used to assess patients’ cognitive functioning. Results: Left-sided cerebellar lesion patients scored lower than controls in attention and visuospatial domain, but not in language, fluency, and memory functions. Participants with right-sided cerebellar lesion demonstrated a general deficit of cognitive functioning, with impairments not only in language and verbal fluency subscales but also in all ACE III domains, including memory, attention, and visuospatial functions. The TMT results proved that cerebellar damage is associated with executive function impairment, regardless of the lesion side. Conclusion: The cognitive profiles of patients with cerebellum lesions differ with regard to the lesion side. Left-sided cerebellar lesions are associated with selective visuospatial and attention impairments, whereas the right-sided ones may result in a more global cognitive decline, which is likely secondary to language deficiencies, associated with this lateral cerebellar injury. Frontiers Media S.A. 2021-12-10 /pmc/articles/PMC8703197/ /pubmed/34955995 http://dx.doi.org/10.3389/fpsyg.2021.775308 Text en Copyright © 2021 Starowicz-Filip, Prochwicz, Kłosowska, Chrobak, Myszka, Bętkowska-Korpała and Kwinta. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Starowicz-Filip, Anna
Prochwicz, Katarzyna
Kłosowska, Joanna
Chrobak, Adrian Andrzej
Myszka, Aneta
Bętkowska-Korpała, Barbara
Kwinta, Borys
Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology
title Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology
title_full Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology
title_fullStr Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology
title_full_unstemmed Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology
title_short Cerebellar Functional Lateralization From the Perspective of Clinical Neuropsychology
title_sort cerebellar functional lateralization from the perspective of clinical neuropsychology
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703197/
https://www.ncbi.nlm.nih.gov/pubmed/34955995
http://dx.doi.org/10.3389/fpsyg.2021.775308
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