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1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints

BACKGROUND: Missing or incomplete phenotypic information can severely deteriorate the statistical power in epidemiological studies. High-throughput quantification of small-molecules in bio-samples, i.e. ‘metabolomics’, is steadily gaining popularity, as it is highly informative for various phenotypi...

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Detalles Bibliográficos
Autores principales: Bizzarri, D., Reinders, M.J.T., Beekman, M., Slagboom, P.E., BBMRI-NL, van den Akker, E.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703237/
https://www.ncbi.nlm.nih.gov/pubmed/34942446
http://dx.doi.org/10.1016/j.ebiom.2021.103764

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