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Colonic Delivery of Celastrol-Loaded Layer-by-Layer Liposomes with Pectin/Trimethylated Chitosan Coating to Enhance Its Anti-Ulcerative Colitis Effects

Herein, a flexible oral colon-targeting delivery system, mediated by electrostatic layer-by-layer alternate deposition with pectin-trimethyl chitosan (TMC) onto liposomes-loading celastrol (Cel/PT-LbL Lipo), was fabricated to enhance anti-UC efficacy. Along with layer-by-layer coating, Cel/Lipo exhi...

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Detalles Bibliográficos
Autores principales:	Xian, Jing, Zhong, Xuemei, Gu, Huan, Wang, Xiao, Li, Jiaxin, Li, Jingjing, Wu, Yihan, Zhang, Chen, Zhang, Jinming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703354/ https://www.ncbi.nlm.nih.gov/pubmed/34959287 http://dx.doi.org/10.3390/pharmaceutics13122005

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