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Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women
Background. Globally, Sexually Transmitted Infections (STIs) are a major cause of morbidity in sexually active individuals, having complications in reproduction health and quality of life. In concordance with the Sustainable Development Goals (SDG), the study aimed to investigate the prevalence of C...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703509/ https://www.ncbi.nlm.nih.gov/pubmed/34959573 http://dx.doi.org/10.3390/pathogens10121618 |
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author | Hernández-Rosas, Fabiola Rey-Barrera, Manuel Conejo-Saucedo, Ulises Orozco-Hernández, Erika Maza-Sánchez, Liliana Navarro-Vidal, Enrique López-Vera, Yasmín Ascencio-Gordillo, María del Carmen de León-Bautista, Mercedes Piedad |
author_facet | Hernández-Rosas, Fabiola Rey-Barrera, Manuel Conejo-Saucedo, Ulises Orozco-Hernández, Erika Maza-Sánchez, Liliana Navarro-Vidal, Enrique López-Vera, Yasmín Ascencio-Gordillo, María del Carmen de León-Bautista, Mercedes Piedad |
author_sort | Hernández-Rosas, Fabiola |
collection | PubMed |
description | Background. Globally, Sexually Transmitted Infections (STIs) are a major cause of morbidity in sexually active individuals, having complications in reproduction health and quality of life. In concordance with the Sustainable Development Goals (SDG), the study aimed to investigate the prevalence of Candida spp., Ureaplasma spp., Trichomonas vaginalis, Neisseria gonorrhoeae, Chlamydia trachomatis, HSV, and Mycoplasma spp. from cervicovaginal samples and to correlate them with the gynecological history of the patients. Methods. Our analytical, prospective, and cross-sectional study included 377 women who participated in a reproductive health campaign during 2015–2016. Anthropometric and gynecological variables were obtained. Cervicovaginal specimens were collected and analyzed with a multiplex in-house PCR to detect Candida spp., Ureaplasma spp., Trichomonas vaginalis, Neisseria gonorrhoeae, HSV, Mycoplasma spp., and Chlamydia trachomatis. Results. The positive cases were 175/377 (46.4%) to at least one of the microorganisms. The most frequent pathogen detected in this population was Ureaplasma spp. (n = 111, 29.4%), followed by Mycoplasma spp. (n = 56, 14.9%) and Candida spp. (n = 47, 12.5%); 33.7% of the positive cases were single infections, whereas 12.7% had coinfection. The multiplex PCR assay was designed targeting nucleotide sequences. Conclusions. Our data demonstrated that monitoring STIs among asymptomatic patients will encourage target programs to be more precisely and effectively implemented, as well as make these programs more affordable, to benefit society by decreasing the prevalence of STIs. |
format | Online Article Text |
id | pubmed-8703509 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87035092021-12-25 Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women Hernández-Rosas, Fabiola Rey-Barrera, Manuel Conejo-Saucedo, Ulises Orozco-Hernández, Erika Maza-Sánchez, Liliana Navarro-Vidal, Enrique López-Vera, Yasmín Ascencio-Gordillo, María del Carmen de León-Bautista, Mercedes Piedad Pathogens Article Background. Globally, Sexually Transmitted Infections (STIs) are a major cause of morbidity in sexually active individuals, having complications in reproduction health and quality of life. In concordance with the Sustainable Development Goals (SDG), the study aimed to investigate the prevalence of Candida spp., Ureaplasma spp., Trichomonas vaginalis, Neisseria gonorrhoeae, Chlamydia trachomatis, HSV, and Mycoplasma spp. from cervicovaginal samples and to correlate them with the gynecological history of the patients. Methods. Our analytical, prospective, and cross-sectional study included 377 women who participated in a reproductive health campaign during 2015–2016. Anthropometric and gynecological variables were obtained. Cervicovaginal specimens were collected and analyzed with a multiplex in-house PCR to detect Candida spp., Ureaplasma spp., Trichomonas vaginalis, Neisseria gonorrhoeae, HSV, Mycoplasma spp., and Chlamydia trachomatis. Results. The positive cases were 175/377 (46.4%) to at least one of the microorganisms. The most frequent pathogen detected in this population was Ureaplasma spp. (n = 111, 29.4%), followed by Mycoplasma spp. (n = 56, 14.9%) and Candida spp. (n = 47, 12.5%); 33.7% of the positive cases were single infections, whereas 12.7% had coinfection. The multiplex PCR assay was designed targeting nucleotide sequences. Conclusions. Our data demonstrated that monitoring STIs among asymptomatic patients will encourage target programs to be more precisely and effectively implemented, as well as make these programs more affordable, to benefit society by decreasing the prevalence of STIs. MDPI 2021-12-13 /pmc/articles/PMC8703509/ /pubmed/34959573 http://dx.doi.org/10.3390/pathogens10121618 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hernández-Rosas, Fabiola Rey-Barrera, Manuel Conejo-Saucedo, Ulises Orozco-Hernández, Erika Maza-Sánchez, Liliana Navarro-Vidal, Enrique López-Vera, Yasmín Ascencio-Gordillo, María del Carmen de León-Bautista, Mercedes Piedad Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women |
title | Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women |
title_full | Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women |
title_fullStr | Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women |
title_full_unstemmed | Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women |
title_short | Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women |
title_sort | monitoring sexually transmitted infections in cervicovaginal exfoliative samples in mexican women |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703509/ https://www.ncbi.nlm.nih.gov/pubmed/34959573 http://dx.doi.org/10.3390/pathogens10121618 |
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