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Cryo-EM Structures of Two Bacteriophage Portal Proteins Provide Insights for Antimicrobial Phage Engineering

Widespread antibiotic resistance has returned attention to bacteriophages as a means of managing bacterial pathogenesis. Synthetic biology approaches to engineer phages have demonstrated genomic editing to broaden natural host ranges, or to optimise microbicidal action. Gram positive pathogens cause...

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Detalles Bibliográficos
Autores principales: Javed, Abid, Villanueva, Hugo, Shataer, Shadikejiang, Vasciaveo, Sara, Savva, Renos, Orlova, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703570/
https://www.ncbi.nlm.nih.gov/pubmed/34960800
http://dx.doi.org/10.3390/v13122532

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