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In Vitro Comparative Study of Solid Lipid and PLGA Nanoparticles Designed to Facilitate Nose-to-Brain Delivery of Insulin
The brain insulin metabolism alteration has been addressed as a pathophysiological factor underlying Alzheimer’s disease (AD). Insulin can be beneficial in AD, but its macro-polypeptide nature negatively influences the chances of reaching the brain. The intranasal (IN) administration of therapeutics...
Autores principales: | Akel, Hussein, Csóka, Ildikó, Ambrus, Rita, Bocsik, Alexandra, Gróf, Ilona, Mészáros, Mária, Szecskó, Anikó, Kozma, Gábor, Veszelka, Szilvia, Deli, Mária A., Kónya, Zoltán, Katona, Gábor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703723/ https://www.ncbi.nlm.nih.gov/pubmed/34948054 http://dx.doi.org/10.3390/ijms222413258 |
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