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Use of Microfluidic Capillary Electrophoresis for the Determination of Multi-Component Protein Adsorption Isotherms: Application to High-Throughput Analysis for Hydrophobic Interaction Chromatography

Chromatography is a widely used separation process for purification of biopharmaceuticals that is able to obtain high purities and concentrations. The phenomena that occur during separation, mass transfer and adsorption are quite complex. To better understand these phenomena and their mechanisms, mu...

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Detalles Bibliográficos
Autores principales: Lietta, Elena, Pieri, Alessandro, Innocenti, Elisa, Pisano, Roberto, Vanni, Marco, Barresi, Antonello A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703794/
https://www.ncbi.nlm.nih.gov/pubmed/34959416
http://dx.doi.org/10.3390/pharmaceutics13122135