Cargando…

Occurrence and Risk Assessment of Dietary Exposure to Deoxynivalenol in Wheat-Based Products Based Different Wheat-Producing Area for the Inhabitants in Shanghai, China

Deoxynivalenol (DON) is one of the major mycotoxins that contaminate cereals. In this study, we determined the DON level in wheat-based products from Chinese five main production areas collected in Shanghai and calculated the daily intake of DON for inhabitants using the point evaluation and the pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Xianli, Zhao, Zhiyong, Wang, Jianhua, Yang, Junhua, E, Hengchao, Chen, Bo, He, Pengzhen, Tan, Yanglan, Zhou, Changyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703861/
https://www.ncbi.nlm.nih.gov/pubmed/34946997
http://dx.doi.org/10.3390/jof7121015
_version_ 1784621567031902208
author Yang, Xianli
Zhao, Zhiyong
Wang, Jianhua
Yang, Junhua
E, Hengchao
Chen, Bo
He, Pengzhen
Tan, Yanglan
Zhou, Changyan
author_facet Yang, Xianli
Zhao, Zhiyong
Wang, Jianhua
Yang, Junhua
E, Hengchao
Chen, Bo
He, Pengzhen
Tan, Yanglan
Zhou, Changyan
author_sort Yang, Xianli
collection PubMed
description Deoxynivalenol (DON) is one of the major mycotoxins that contaminate cereals. In this study, we determined the DON level in wheat-based products from Chinese five main production areas collected in Shanghai and calculated the daily intake of DON for inhabitants using the point evaluation and the probabilistic evaluation based on Monte Carlo simulation. The results showed the positive rates of DON in the products were higher than 80.0%, with the concentrations ranging from 41.8 to 1110 µg/kg. The estimated mean daily intakes of DON for 7- to 10-year-old children and adults groups were below 1 µg/kg bw/day, the provisional maximum tolerable daily intake (PMTDI) set by the Joint FAO/WHO Expert Committee on Food Additives (JECFA), suggesting no health risks for the consumers. However, the 99th percentiles of dietary DON exposures for children and adults exceeded the PMTDI, indicating adverse health effects might occur if the two groups intake highly contaminated wheat-based products. The potential health risks for the two groups exposed to DON in the wheat-based products from the Middle and Lower Yangtze Valley (MLYV) were higher than those from the other areas in China.
format Online
Article
Text
id pubmed-8703861
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-87038612021-12-25 Occurrence and Risk Assessment of Dietary Exposure to Deoxynivalenol in Wheat-Based Products Based Different Wheat-Producing Area for the Inhabitants in Shanghai, China Yang, Xianli Zhao, Zhiyong Wang, Jianhua Yang, Junhua E, Hengchao Chen, Bo He, Pengzhen Tan, Yanglan Zhou, Changyan J Fungi (Basel) Article Deoxynivalenol (DON) is one of the major mycotoxins that contaminate cereals. In this study, we determined the DON level in wheat-based products from Chinese five main production areas collected in Shanghai and calculated the daily intake of DON for inhabitants using the point evaluation and the probabilistic evaluation based on Monte Carlo simulation. The results showed the positive rates of DON in the products were higher than 80.0%, with the concentrations ranging from 41.8 to 1110 µg/kg. The estimated mean daily intakes of DON for 7- to 10-year-old children and adults groups were below 1 µg/kg bw/day, the provisional maximum tolerable daily intake (PMTDI) set by the Joint FAO/WHO Expert Committee on Food Additives (JECFA), suggesting no health risks for the consumers. However, the 99th percentiles of dietary DON exposures for children and adults exceeded the PMTDI, indicating adverse health effects might occur if the two groups intake highly contaminated wheat-based products. The potential health risks for the two groups exposed to DON in the wheat-based products from the Middle and Lower Yangtze Valley (MLYV) were higher than those from the other areas in China. MDPI 2021-11-26 /pmc/articles/PMC8703861/ /pubmed/34946997 http://dx.doi.org/10.3390/jof7121015 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Xianli
Zhao, Zhiyong
Wang, Jianhua
Yang, Junhua
E, Hengchao
Chen, Bo
He, Pengzhen
Tan, Yanglan
Zhou, Changyan
Occurrence and Risk Assessment of Dietary Exposure to Deoxynivalenol in Wheat-Based Products Based Different Wheat-Producing Area for the Inhabitants in Shanghai, China
title Occurrence and Risk Assessment of Dietary Exposure to Deoxynivalenol in Wheat-Based Products Based Different Wheat-Producing Area for the Inhabitants in Shanghai, China
title_full Occurrence and Risk Assessment of Dietary Exposure to Deoxynivalenol in Wheat-Based Products Based Different Wheat-Producing Area for the Inhabitants in Shanghai, China
title_fullStr Occurrence and Risk Assessment of Dietary Exposure to Deoxynivalenol in Wheat-Based Products Based Different Wheat-Producing Area for the Inhabitants in Shanghai, China
title_full_unstemmed Occurrence and Risk Assessment of Dietary Exposure to Deoxynivalenol in Wheat-Based Products Based Different Wheat-Producing Area for the Inhabitants in Shanghai, China
title_short Occurrence and Risk Assessment of Dietary Exposure to Deoxynivalenol in Wheat-Based Products Based Different Wheat-Producing Area for the Inhabitants in Shanghai, China
title_sort occurrence and risk assessment of dietary exposure to deoxynivalenol in wheat-based products based different wheat-producing area for the inhabitants in shanghai, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703861/
https://www.ncbi.nlm.nih.gov/pubmed/34946997
http://dx.doi.org/10.3390/jof7121015
work_keys_str_mv AT yangxianli occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina
AT zhaozhiyong occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina
AT wangjianhua occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina
AT yangjunhua occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina
AT ehengchao occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina
AT chenbo occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina
AT hepengzhen occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina
AT tanyanglan occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina
AT zhouchangyan occurrenceandriskassessmentofdietaryexposuretodeoxynivalenolinwheatbasedproductsbaseddifferentwheatproducingareafortheinhabitantsinshanghaichina