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An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature

The clinical course of Crohn’s disease (CD) is often complicated by intestinal strictures, which can be fibrotic, inflammatory, or mixed, therefore leading to stenosis and eventually symptomatic obstruction. We report two cases of subclinical CD diagnosed after fruit pit ingestion, causing bowel obs...

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Autores principales: Sinagra, Emanuele, Raimondo, Dario, Iacopinelli, Salvatore Marco, Rossi, Francesca, Conoscenti, Giuseppe, Di Maggio, Maria Angela, Testai, Sergio, Alloro, Rita, Marasà, Marta, Calandra, Alberto, Costanza, Claudia, Cristofalo, Serena, Pallio, Socrate, Maida, Marcello, Tarantino, Ilaria, Arena, Goffredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703957/
https://www.ncbi.nlm.nih.gov/pubmed/34947946
http://dx.doi.org/10.3390/life11121415
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author Sinagra, Emanuele
Raimondo, Dario
Iacopinelli, Salvatore Marco
Rossi, Francesca
Conoscenti, Giuseppe
Di Maggio, Maria Angela
Testai, Sergio
Alloro, Rita
Marasà, Marta
Calandra, Alberto
Costanza, Claudia
Cristofalo, Serena
Pallio, Socrate
Maida, Marcello
Tarantino, Ilaria
Arena, Goffredo
author_facet Sinagra, Emanuele
Raimondo, Dario
Iacopinelli, Salvatore Marco
Rossi, Francesca
Conoscenti, Giuseppe
Di Maggio, Maria Angela
Testai, Sergio
Alloro, Rita
Marasà, Marta
Calandra, Alberto
Costanza, Claudia
Cristofalo, Serena
Pallio, Socrate
Maida, Marcello
Tarantino, Ilaria
Arena, Goffredo
author_sort Sinagra, Emanuele
collection PubMed
description The clinical course of Crohn’s disease (CD) is often complicated by intestinal strictures, which can be fibrotic, inflammatory, or mixed, therefore leading to stenosis and eventually symptomatic obstruction. We report two cases of subclinical CD diagnosed after fruit pit ingestion, causing bowel obstruction; additionally, we conducted a narrative review of the scientific literature on cases of intestinal obstruction secondary to impacted bezoars due to fruit pits. Symptoms of gastrointestinal bezoars in CD patients are not diagnostic; and the diagnosis should be based on a combined assessment of history, clinical presentation, imaging examination and endoscopy findings. This report corroborates the concept that CD patients are at a greater risk of bowel obstruction with bezoars generally and shows that accidental ingestion of fruit pits may lead to an unusual presentation of the disease. Therapeutic options in this group of patients differ from the usual approaches implemented in other patients with strictures secondary to CD.
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spelling pubmed-87039572021-12-25 An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature Sinagra, Emanuele Raimondo, Dario Iacopinelli, Salvatore Marco Rossi, Francesca Conoscenti, Giuseppe Di Maggio, Maria Angela Testai, Sergio Alloro, Rita Marasà, Marta Calandra, Alberto Costanza, Claudia Cristofalo, Serena Pallio, Socrate Maida, Marcello Tarantino, Ilaria Arena, Goffredo Life (Basel) Case Report The clinical course of Crohn’s disease (CD) is often complicated by intestinal strictures, which can be fibrotic, inflammatory, or mixed, therefore leading to stenosis and eventually symptomatic obstruction. We report two cases of subclinical CD diagnosed after fruit pit ingestion, causing bowel obstruction; additionally, we conducted a narrative review of the scientific literature on cases of intestinal obstruction secondary to impacted bezoars due to fruit pits. Symptoms of gastrointestinal bezoars in CD patients are not diagnostic; and the diagnosis should be based on a combined assessment of history, clinical presentation, imaging examination and endoscopy findings. This report corroborates the concept that CD patients are at a greater risk of bowel obstruction with bezoars generally and shows that accidental ingestion of fruit pits may lead to an unusual presentation of the disease. Therapeutic options in this group of patients differ from the usual approaches implemented in other patients with strictures secondary to CD. MDPI 2021-12-16 /pmc/articles/PMC8703957/ /pubmed/34947946 http://dx.doi.org/10.3390/life11121415 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Sinagra, Emanuele
Raimondo, Dario
Iacopinelli, Salvatore Marco
Rossi, Francesca
Conoscenti, Giuseppe
Di Maggio, Maria Angela
Testai, Sergio
Alloro, Rita
Marasà, Marta
Calandra, Alberto
Costanza, Claudia
Cristofalo, Serena
Pallio, Socrate
Maida, Marcello
Tarantino, Ilaria
Arena, Goffredo
An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature
title An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature
title_full An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature
title_fullStr An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature
title_full_unstemmed An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature
title_short An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature
title_sort unusual presentation of crohn’s disease diagnosed following accidental ingestion of fruit pits: report of two cases and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703957/
https://www.ncbi.nlm.nih.gov/pubmed/34947946
http://dx.doi.org/10.3390/life11121415
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