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An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature
The clinical course of Crohn’s disease (CD) is often complicated by intestinal strictures, which can be fibrotic, inflammatory, or mixed, therefore leading to stenosis and eventually symptomatic obstruction. We report two cases of subclinical CD diagnosed after fruit pit ingestion, causing bowel obs...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703957/ https://www.ncbi.nlm.nih.gov/pubmed/34947946 http://dx.doi.org/10.3390/life11121415 |
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author | Sinagra, Emanuele Raimondo, Dario Iacopinelli, Salvatore Marco Rossi, Francesca Conoscenti, Giuseppe Di Maggio, Maria Angela Testai, Sergio Alloro, Rita Marasà, Marta Calandra, Alberto Costanza, Claudia Cristofalo, Serena Pallio, Socrate Maida, Marcello Tarantino, Ilaria Arena, Goffredo |
author_facet | Sinagra, Emanuele Raimondo, Dario Iacopinelli, Salvatore Marco Rossi, Francesca Conoscenti, Giuseppe Di Maggio, Maria Angela Testai, Sergio Alloro, Rita Marasà, Marta Calandra, Alberto Costanza, Claudia Cristofalo, Serena Pallio, Socrate Maida, Marcello Tarantino, Ilaria Arena, Goffredo |
author_sort | Sinagra, Emanuele |
collection | PubMed |
description | The clinical course of Crohn’s disease (CD) is often complicated by intestinal strictures, which can be fibrotic, inflammatory, or mixed, therefore leading to stenosis and eventually symptomatic obstruction. We report two cases of subclinical CD diagnosed after fruit pit ingestion, causing bowel obstruction; additionally, we conducted a narrative review of the scientific literature on cases of intestinal obstruction secondary to impacted bezoars due to fruit pits. Symptoms of gastrointestinal bezoars in CD patients are not diagnostic; and the diagnosis should be based on a combined assessment of history, clinical presentation, imaging examination and endoscopy findings. This report corroborates the concept that CD patients are at a greater risk of bowel obstruction with bezoars generally and shows that accidental ingestion of fruit pits may lead to an unusual presentation of the disease. Therapeutic options in this group of patients differ from the usual approaches implemented in other patients with strictures secondary to CD. |
format | Online Article Text |
id | pubmed-8703957 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87039572021-12-25 An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature Sinagra, Emanuele Raimondo, Dario Iacopinelli, Salvatore Marco Rossi, Francesca Conoscenti, Giuseppe Di Maggio, Maria Angela Testai, Sergio Alloro, Rita Marasà, Marta Calandra, Alberto Costanza, Claudia Cristofalo, Serena Pallio, Socrate Maida, Marcello Tarantino, Ilaria Arena, Goffredo Life (Basel) Case Report The clinical course of Crohn’s disease (CD) is often complicated by intestinal strictures, which can be fibrotic, inflammatory, or mixed, therefore leading to stenosis and eventually symptomatic obstruction. We report two cases of subclinical CD diagnosed after fruit pit ingestion, causing bowel obstruction; additionally, we conducted a narrative review of the scientific literature on cases of intestinal obstruction secondary to impacted bezoars due to fruit pits. Symptoms of gastrointestinal bezoars in CD patients are not diagnostic; and the diagnosis should be based on a combined assessment of history, clinical presentation, imaging examination and endoscopy findings. This report corroborates the concept that CD patients are at a greater risk of bowel obstruction with bezoars generally and shows that accidental ingestion of fruit pits may lead to an unusual presentation of the disease. Therapeutic options in this group of patients differ from the usual approaches implemented in other patients with strictures secondary to CD. MDPI 2021-12-16 /pmc/articles/PMC8703957/ /pubmed/34947946 http://dx.doi.org/10.3390/life11121415 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Sinagra, Emanuele Raimondo, Dario Iacopinelli, Salvatore Marco Rossi, Francesca Conoscenti, Giuseppe Di Maggio, Maria Angela Testai, Sergio Alloro, Rita Marasà, Marta Calandra, Alberto Costanza, Claudia Cristofalo, Serena Pallio, Socrate Maida, Marcello Tarantino, Ilaria Arena, Goffredo An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature |
title | An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature |
title_full | An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature |
title_fullStr | An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature |
title_full_unstemmed | An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature |
title_short | An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature |
title_sort | unusual presentation of crohn’s disease diagnosed following accidental ingestion of fruit pits: report of two cases and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703957/ https://www.ncbi.nlm.nih.gov/pubmed/34947946 http://dx.doi.org/10.3390/life11121415 |
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