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In Vitro Activity of Monofunctional Pt-II Complex Based on 8-Aminoquinoline against Human Glioblastoma

A new cationic Pt(II) complex bearing 8-aminoquinoline as chelating ligand (called Pt-8AQ) was evaluated against two human carcinomas, one mesothelioma, and three glioblastoma cell lines. The in vitro comparison to the clinically approved CisPt showed a minor activity of Pt-8AQ against carcinoma and...

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Detalles Bibliográficos
Autores principales: Coccè, Valentina, Rimoldi, Isabella, Facchetti, Giorgio, Ciusani, Emilio, Alessandri, Giulio, Signorini, Lucia, Sisto, Francesca, Giannì, Aldo, Paino, Francesca, Pessina, Augusto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704014/
https://www.ncbi.nlm.nih.gov/pubmed/34959382
http://dx.doi.org/10.3390/pharmaceutics13122101