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Origin of Proteolytic Stability of Peptide-Brush Polymers as Globular Proteomimetics

[Image: see text] Peptide-brush polymers (PBPs), wherein every side-chain of the polymers is peptidic, represent a new class of proteomimetic with unusually high proteolytic resistance while maintaining bioactivity. Here, we sought to determine the origin of this behavior and to assess its generalit...

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Detalles Bibliográficos
Autores principales: Sun, Hao, Qiao, Baofu, Choi, Wonmin, Hampu, Nicholas, McCallum, Naneki C., Thompson, Matthew P., Oktawiec, Julia, Weigand, Steven, Ebrahim, Omar M., de la Cruz, Monica Olvera, Gianneschi, Nathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704038/
https://www.ncbi.nlm.nih.gov/pubmed/34963898
http://dx.doi.org/10.1021/acscentsci.1c01149