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A Metabolomics Approach to Increasing Chinese Hamster Ovary (CHO) Cell Productivity

Much progress has been made in improving the viable cell density of bioreactor cultures in monoclonal antibody production from Chinese hamster ovary (CHO) cells; however, specific productivity (qP) has not been increased to the same degree. In this work, we analyzed a library of 24 antibody-expressi...

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Detalles Bibliográficos
Autores principales: Yao, Grace, Aron, Kathryn, Borys, Michael, Li, Zhengjian, Pendse, Girish, Lee, Kyongbum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704136/
https://www.ncbi.nlm.nih.gov/pubmed/34940581
http://dx.doi.org/10.3390/metabo11120823