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Investigating Structural Property Relationships to Enable Repurposing of Pharmaceuticals as Zinc Ionophores

The importance of zinc in biology has gained greater recognition in recent years due to its essential contributions to the function of many endogenous enzymes. Disruption of zinc homeostasis may be useful in treating pathological conditions, such as Alzheimer’s, and for antiviral purposes. Despite t...

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Detalles Bibliográficos
Autores principales: Kavanagh, Oisín, Elmes, Robert, O’Sullivan, Finbarr, Farragher, John, Robinson, Shane, Walker, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704213/
https://www.ncbi.nlm.nih.gov/pubmed/34959313
http://dx.doi.org/10.3390/pharmaceutics13122032