Cargando…
Investigating Structural Property Relationships to Enable Repurposing of Pharmaceuticals as Zinc Ionophores
The importance of zinc in biology has gained greater recognition in recent years due to its essential contributions to the function of many endogenous enzymes. Disruption of zinc homeostasis may be useful in treating pathological conditions, such as Alzheimer’s, and for antiviral purposes. Despite t...
Autores principales: | Kavanagh, Oisín, Elmes, Robert, O’Sullivan, Finbarr, Farragher, John, Robinson, Shane, Walker, Gavin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704213/ https://www.ncbi.nlm.nih.gov/pubmed/34959313 http://dx.doi.org/10.3390/pharmaceutics13122032 |
Ejemplares similares
-
Hydroxychloroquine Does Not Function as a Direct Zinc Ionophore
por: Kavanagh, Oisín N., et al.
Publicado: (2022) -
Chloroquine Is a Zinc Ionophore
por: Xue, Jing, et al.
Publicado: (2014) -
Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2
por: Harbison-Price, Nichaela, et al.
Publicado: (2020) -
Inhaled hydroxychloroquine to improve efficacy and reduce harm in the treatment of COVID-19
por: Kavanagh, Oisín, et al.
Publicado: (2020) -
Umbelliferyloxymethyl phosphonate compounds-weakly binding zinc ionophores with neuroprotective properties
por: Guesne, Sebastien, et al.
Publicado: (2021)