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Lactobacillus acidophilus Supplementation Exerts a Synergistic Effect on Tacrolimus Efficacy by Modulating Th17/Treg Balance in Lupus-Prone Mice via the SIGNR3 Pathway

OBJECTIVE: Tacrolimus (Tac) is an immunosuppressant used in the treatment of systemic lupus erythematosus (SLE); however, it induces T cell subset imbalances by reducing regulatory T (Treg) cells. Lactobacillus acidophilus (LA) is reported to have therapeutic efficacy in immune-mediated diseases via...

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Detalles Bibliográficos
Autores principales:	Kim, Da Som, Park, Youngjae, Choi, Jeong-Won, Park, Sung-Hwan, Cho, Mi-La, Kwok, Seung-Ki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704231/ https://www.ncbi.nlm.nih.gov/pubmed/34956169 http://dx.doi.org/10.3389/fimmu.2021.696074

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