Cargando…

Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study

To date, it is still unclear how fresh osteoporotic vertebral fractures (OVFs) affect the patient’s quality of life and low back pain during a follow-up period of more than 1 year. In the previous trial, women with fresh OVF were randomized to rigid or soft brace for 12 weeks, then both groups were...

Descripción completa

Detalles Bibliográficos
Autores principales: Inose, Hiroyuki, Kato, Tsuyoshi, Shirasawa, Shinichi, Takahashi, Shinji, Hoshino, Masatoshi, Yamato, Yu, Matsukura, Yu, Hirai, Takashi, Yoshii, Toshitaka, Okawa, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704362/
https://www.ncbi.nlm.nih.gov/pubmed/34945257
http://dx.doi.org/10.3390/jcm10245961
_version_ 1784621689537036288
author Inose, Hiroyuki
Kato, Tsuyoshi
Shirasawa, Shinichi
Takahashi, Shinji
Hoshino, Masatoshi
Yamato, Yu
Matsukura, Yu
Hirai, Takashi
Yoshii, Toshitaka
Okawa, Atsushi
author_facet Inose, Hiroyuki
Kato, Tsuyoshi
Shirasawa, Shinichi
Takahashi, Shinji
Hoshino, Masatoshi
Yamato, Yu
Matsukura, Yu
Hirai, Takashi
Yoshii, Toshitaka
Okawa, Atsushi
author_sort Inose, Hiroyuki
collection PubMed
description To date, it is still unclear how fresh osteoporotic vertebral fractures (OVFs) affect the patient’s quality of life and low back pain during a follow-up period of more than 1 year. In the previous trial, women with fresh OVF were randomized to rigid or soft brace for 12 weeks, then both groups were followed for the subsequent 48 weeks. In women completing this trial at our affiliated hospitals, we conducted a follow-up study to investigate the long-term course of an acute vertebral fracture in terms of pain and quality of life. When comparing visual analog scale scores for low back pain and European Quality of Life-5 Dimensions Questionnaire scores between consecutive time points, a significant difference was found between 0 and 12 weeks, but not between 12 and 48 weeks or between 48 weeks and final follow-up. A total 25% had residual low back pain at the final follow-up. A stepwise logistic regression analysis identified age and previous vertebral fracture as predictors of residual low back pain at the final follow-up. Therefore, the degree of low back pain and impairment of the quality of life improved by 12 weeks after injury and did not change thereafter until a mean follow-up of 5.3 years.
format Online
Article
Text
id pubmed-8704362
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-87043622021-12-25 Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study Inose, Hiroyuki Kato, Tsuyoshi Shirasawa, Shinichi Takahashi, Shinji Hoshino, Masatoshi Yamato, Yu Matsukura, Yu Hirai, Takashi Yoshii, Toshitaka Okawa, Atsushi J Clin Med Article To date, it is still unclear how fresh osteoporotic vertebral fractures (OVFs) affect the patient’s quality of life and low back pain during a follow-up period of more than 1 year. In the previous trial, women with fresh OVF were randomized to rigid or soft brace for 12 weeks, then both groups were followed for the subsequent 48 weeks. In women completing this trial at our affiliated hospitals, we conducted a follow-up study to investigate the long-term course of an acute vertebral fracture in terms of pain and quality of life. When comparing visual analog scale scores for low back pain and European Quality of Life-5 Dimensions Questionnaire scores between consecutive time points, a significant difference was found between 0 and 12 weeks, but not between 12 and 48 weeks or between 48 weeks and final follow-up. A total 25% had residual low back pain at the final follow-up. A stepwise logistic regression analysis identified age and previous vertebral fracture as predictors of residual low back pain at the final follow-up. Therefore, the degree of low back pain and impairment of the quality of life improved by 12 weeks after injury and did not change thereafter until a mean follow-up of 5.3 years. MDPI 2021-12-19 /pmc/articles/PMC8704362/ /pubmed/34945257 http://dx.doi.org/10.3390/jcm10245961 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Inose, Hiroyuki
Kato, Tsuyoshi
Shirasawa, Shinichi
Takahashi, Shinji
Hoshino, Masatoshi
Yamato, Yu
Matsukura, Yu
Hirai, Takashi
Yoshii, Toshitaka
Okawa, Atsushi
Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study
title Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study
title_full Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study
title_fullStr Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study
title_full_unstemmed Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study
title_short Time Course of Acute Vertebral Fractures: A Prospective Multicenter Cohort Study
title_sort time course of acute vertebral fractures: a prospective multicenter cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704362/
https://www.ncbi.nlm.nih.gov/pubmed/34945257
http://dx.doi.org/10.3390/jcm10245961
work_keys_str_mv AT inosehiroyuki timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT katotsuyoshi timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT shirasawashinichi timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT takahashishinji timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT hoshinomasatoshi timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT yamatoyu timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT matsukurayu timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT hiraitakashi timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT yoshiitoshitaka timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy
AT okawaatsushi timecourseofacutevertebralfracturesaprospectivemulticentercohortstudy