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Analysis of Antidepressant-like Effects and Action Mechanisms of GSB-106, a Small Molecule, Affecting the TrkB Signaling

Induction of BDNF-TrkB signaling is associated with the action mechanisms of conventional and fast-acting antidepressants. GSB-106, developed as a small dimeric dipeptide mimetic of BDNF, was previously shown to produce antidepressant-like effects in the mouse Porsolt test, tail suspension test, Nom...

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Detalles Bibliográficos
Autores principales: Vakhitova, Yulia V., Kalinina, Tatiana S., Zainullina, Liana F., Lusta, Anastasiya Yu., Volkova, Anna V., Kudryashov, Nikita V., Gudasheva, Tatiana A., Shimshirt, Alexander A., Kadnikov, Ilya A., Voronin, Mikhail V., Seredenin, Sergei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704497/
https://www.ncbi.nlm.nih.gov/pubmed/34948177
http://dx.doi.org/10.3390/ijms222413381