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Analysis of Antidepressant-like Effects and Action Mechanisms of GSB-106, a Small Molecule, Affecting the TrkB Signaling
Induction of BDNF-TrkB signaling is associated with the action mechanisms of conventional and fast-acting antidepressants. GSB-106, developed as a small dimeric dipeptide mimetic of BDNF, was previously shown to produce antidepressant-like effects in the mouse Porsolt test, tail suspension test, Nom...
Autores principales: | Vakhitova, Yulia V., Kalinina, Tatiana S., Zainullina, Liana F., Lusta, Anastasiya Yu., Volkova, Anna V., Kudryashov, Nikita V., Gudasheva, Tatiana A., Shimshirt, Alexander A., Kadnikov, Ilya A., Voronin, Mikhail V., Seredenin, Sergei B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704497/ https://www.ncbi.nlm.nih.gov/pubmed/34948177 http://dx.doi.org/10.3390/ijms222413381 |
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