Development, Characterization, Optimization, and In Vivo Evaluation of Methacrylic Acid–Ethyl Acrylate Copolymer Nanoparticles Loaded with Glibenclamide in Diabetic Rats for Oral Administration

The methacrylic acid–ethyl acrylate copolymer nanoparticles were prepared using the solvent displacement method. The independent variables were the drug/polymer ratio, surfactant concentration, Polioxyl 40 hydrogenated castor oil, the added water volume, time, and stirring speed, while size, PDI, ze...

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Detalles Bibliográficos
Autores principales: Guadarrama-Escobar, Omar Rodrigo, Sánchez-Vázquez, Ivonne, Serrano-Castañeda, Pablo, Chamorro-Cevallos, German Alberto, Rodríguez-Cruz, Isabel Marlen, Sánchez-Padrón, Adalí Yisell, Anguiano-Almazán, Ericka, Peña-Juárez, Ma. Concepción, Méndez-Albores, Abraham, Domínguez-Delgado, Clara Luisa, Mercado-Márquez, Crisóforo, Rodríguez-Pérez, Betsabé, Escobar-Chávez, José Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704609/
https://www.ncbi.nlm.nih.gov/pubmed/34959305
http://dx.doi.org/10.3390/pharmaceutics13122023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704609/
https://www.ncbi.nlm.nih.gov/pubmed/34959305
http://dx.doi.org/10.3390/pharmaceutics13122023

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