Cargando…

Novel Naproxen Salts with Increased Skin Permeability

The paper presents the synthesis, full identification, and characterization of new salts-L-proline alkyl ester naproxenates [ProOR][NAP], where R was a chain from ethyl to butyl (including isopropyl). All obtained compounds were characterized by Nuclear Magnetic Resonance (NMR), Fourier transform in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Świątek, Ewelina, Ossowicz-Rupniewska, Paula, Janus, Ewa, Nowak, Anna, Sobolewski, Peter, Duchnik, Wiktoria, Kucharski, Łukasz, Klimowicz, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704648/ https://www.ncbi.nlm.nih.gov/pubmed/34959392 http://dx.doi.org/10.3390/pharmaceutics13122110

Ejemplares similares

Influence of the Type of Amino Acid on the Permeability and Properties of Ibuprofenates of Isopropyl Amino Acid Esters
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2022)

Permeability of Ibuprofen in the Form of Free Acid and Salts of L-Valine Alkyl Esters from a Hydrogel Formulation through Strat-M™ Membrane and Human Skin
por: Klebeko, Joanna, et al.
Publicado: (2021)

Transdermal Delivery Systems for Ibuprofen and Ibuprofen Modified with Amino Acids Alkyl Esters Based on Bacterial Cellulose
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2021)

Enhancement of ibuprofen solubility and skin permeation by conjugation with l-valine alkyl esters
por: Janus, Ewa, et al.
Publicado: (2020)

The effect of alcohols as vehicles on the percutaneous absorption and skin retention of ibuprofen modified with l-valine alkyl esters
por: Ossowicz, Paula, et al.
Publicado: (2020)

Evaluation of the Structural Modification of Ibuprofen on the Penetration Release of Ibuprofen from a Drug-in-Adhesive Matrix Type Transdermal Patch
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2022)

Exploring Alkyl Ester Salts of L-Amino Acid Derivatives of Ibuprofen: Physicochemical Characterization and Transdermal Potential
por: Witkowski, Kordian, et al.
Publicado: (2023)

Epilobium angustifolium L. Essential Oil—Biological Activity and Enhancement of the Skin Penetration of Drugs—In Vitro Study
por: Nowak, Anna, et al.
Publicado: (2021)

Sustainable UV-Crosslinkable Acrylic Pressure-Sensitive Adhesives for Medical Application
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2021)

Enhancing Transdermal Delivery: Investigating the Impact of Permeation Promoters on Ibuprofen Release and Penetration from Medical Patches—In Vitro Research
por: Bednarczyk, Paulina, et al.
Publicado: (2023)

Assessment of the Effect of Structural Modification of Ibuprofen on the Penetration of Ibuprofen from Pentravan(®) (Semisolid) Formulation Using Human Skin and a Transdermal Diffusion Test Model
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2021)

New amino acid propyl ester ibuprofenates from synthesis to use in drug delivery systems
por: Ossowicz-Rupniewska, Paula, et al.
Publicado: (2022)

Bacterial Cellulose Membrane Containing Epilobium angustifolium L. Extract as a Promising Material for the Topical Delivery of Antioxidants to the Skin
por: Nowak, Anna, et al.
Publicado: (2021)

Evaluation of the in vitro permeation parameters of topical ketoprofen and lidocaine hydrochloride from transdermal Pentravan(®) products through human skin
por: Adamiak-Giera, Urszula, et al.
Publicado: (2023)

Assessment of the Anti-Inflammatory, Antibacterial and Anti-Aging Properties and Possible Use on the Skin of Hydrogels Containing Epilobium angustifolium L. Extracts
por: Nowak, Anna, et al.
Publicado: (2022)

Corrigendum: Assessment of the anti-inflammatory, antibacterial and anti-aging properties and possible use on the skin of hydrogels containing Epilobium angustifolium L. extracts
por: Nowak, Anna, et al.
Publicado: (2022)

New Ferulic Acid and Amino Acid Derivatives with Increased Cosmeceutical and Pharmaceutical Potential
por: Janus, Ewa, et al.
Publicado: (2022)

Enhancement of the Antioxidant and Skin Permeation Properties of Betulin and Its Derivatives
por: Günther, Andrzej, et al.
Publicado: (2021)

Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives
por: Makuch, Edyta, et al.
Publicado: (2020)

Epilobium angustifolium L. Extracts as Valuable Ingredients in Cosmetic and Dermatological Products
por: Nowak, Anna, et al.
Publicado: (2021)

The Effect of Cream and Gel Vehicles on the Percutaneous Absorption and Skin Retention of a New Eugenol Derivative With Antioxidant Activity
por: Makuch, Edyta, et al.
Publicado: (2021)

Emulsion-Based Gel Loaded with Ibuprofen and Its Derivatives
por: Agboola, Adebukola Abiola, et al.
Publicado: (2023)

The application of amino acid ionic liquids as additives in the ultrasound-assisted extraction of plant material
por: Roman, Barbara, et al.
Publicado: (2021)

Salicylic Acid as Ionic Liquid Formulation May Have Enhanced Potency to Treat Some Chronic Skin Diseases
por: Klebeko, Joanna, et al.
Publicado: (2021)

Anticancer properties of bacterial cellulose membrane containing ethanolic extract of Epilobium angustifolium L
por: Perużyńska, Magdalena, et al.
Publicado: (2023)

Biodegradation of L-Valine Alkyl Ester Ibuprofenates by Bacterial Cultures
por: Makuch, Edyta, et al.
Publicado: (2021)

Isopropyl Amino Acid Esters Ionic Liquids as Vehicles for Non-Steroidal Anti-Inflammatory Drugs in Potential Topical Drug Delivery Systems with Antimicrobial Activity
por: Klebeko, Joanna, et al.
Publicado: (2022)

Ketoprofen-Based Ionic Liquids: Synthesis and Interactions with Bovine Serum Albumin
por: Ossowicz, Paula, et al.
Publicado: (2019)

Composition and Properties of Protective Coatings Made of Biologically-Derived Polyester Reactive Binder
por: Kugler, Szymon, et al.
Publicado: (2021)

Preparation and Synthetic Application of Naproxen-Containing Diaryliodonium Salts
por: Zhou, Jun, et al.
Publicado: (2021)

Biologically Active Preparations from the Leaves of Wild Plant Species of the Genus Rubus
por: Kucharski, Łukasz, et al.
Publicado: (2022)

Novel Multifunctional Epoxy (Meth)Acrylate Resins and Coatings Preparation via Cationic and Free-Radical Photopolymerization
por: Bednarczyk, Paulina, et al.
Publicado: (2021)

Synthesis of Epoxy Methacrylate Resin and Coatings Preparation by Cationic and Radical Photocrosslinking
por: Bednarczyk, Paulina, et al.
Publicado: (2021)

The Effect of Various Vehicles on the Naproxen Permeability through Rat Skin: A Mechanistic Study by DSC and FT-IR Techniques
por: Salimi, Anayatollah, et al.
Publicado: (2016)

In Vitro Human Skin Penetration, Antioxidant and Antimicrobial Activity of Ethanol-Water Extract of Fireweed (Epilobium angustifolium L.)
por: Nowak, Anna, et al.
Publicado: (2021)

Preparation, Characterization and Study of the Dissociation of Naproxen from Its Chitosan Salt
por: Medeiros, Ricardo S., et al.
Publicado: (2022)

Synthesis of Hybrid Epoxy Methacrylate Resin Based on Diglycidyl Ethers and Coatings Preparation via Cationic and Free-Radical Photopolymerization
por: Bednarczyk, Paulina, et al.
Publicado: (2022)

Impact of the Chemical Structure of Photoreactive Urethane (Meth)Acrylates with Various (Meth)Acrylate Groups and Built-In Diels–Alder Reaction Adducts on the UV-Curing Process and Self-Healing Properties
por: Bednarczyk, Paulina, et al.
Publicado: (2023)

Aldosterone Increases Vascular Permeability in Rat Skin
por: Aleksiejczuk, Michal, et al.
Publicado: (2022)

Photoallergy to Naproxen
por: Rojas Perez-Ezquerra, Patricia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f3l5pbuvvrkbomsvpgd16f7366