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Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features

Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti-inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone...

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Autores principales: Amen, Yhiya, Elsbaey, Marwa, Othman, Ahmed, Sallam, Mahmoud, Shimizu, Kuniyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704703/
https://www.ncbi.nlm.nih.gov/pubmed/34946728
http://dx.doi.org/10.3390/molecules26247646
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author Amen, Yhiya
Elsbaey, Marwa
Othman, Ahmed
Sallam, Mahmoud
Shimizu, Kuniyoshi
author_facet Amen, Yhiya
Elsbaey, Marwa
Othman, Ahmed
Sallam, Mahmoud
Shimizu, Kuniyoshi
author_sort Amen, Yhiya
collection PubMed
description Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti-inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone glycosides, suggesting their potential as drug leads. This review compiles 192 naturally occurring chromone glycosides along with their sources, classification, biological activities, and spectroscopic features. Detailed biosynthetic pathways and chemotaxonomic studies are also described. Extensive spectroscopic features for this class of compounds have been thoroughly discussed, and detailed (13)C-NMR data of compounds 1–192, have been added, except for those that have no reported (13)C-NMR data.
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spelling pubmed-87047032021-12-25 Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features Amen, Yhiya Elsbaey, Marwa Othman, Ahmed Sallam, Mahmoud Shimizu, Kuniyoshi Molecules Review Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti-inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone glycosides, suggesting their potential as drug leads. This review compiles 192 naturally occurring chromone glycosides along with their sources, classification, biological activities, and spectroscopic features. Detailed biosynthetic pathways and chemotaxonomic studies are also described. Extensive spectroscopic features for this class of compounds have been thoroughly discussed, and detailed (13)C-NMR data of compounds 1–192, have been added, except for those that have no reported (13)C-NMR data. MDPI 2021-12-16 /pmc/articles/PMC8704703/ /pubmed/34946728 http://dx.doi.org/10.3390/molecules26247646 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Amen, Yhiya
Elsbaey, Marwa
Othman, Ahmed
Sallam, Mahmoud
Shimizu, Kuniyoshi
Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features
title Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features
title_full Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features
title_fullStr Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features
title_full_unstemmed Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features
title_short Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features
title_sort naturally occurring chromone glycosides: sources, bioactivities, and spectroscopic features
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704703/
https://www.ncbi.nlm.nih.gov/pubmed/34946728
http://dx.doi.org/10.3390/molecules26247646
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