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Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features
Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti-inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704703/ https://www.ncbi.nlm.nih.gov/pubmed/34946728 http://dx.doi.org/10.3390/molecules26247646 |
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author | Amen, Yhiya Elsbaey, Marwa Othman, Ahmed Sallam, Mahmoud Shimizu, Kuniyoshi |
author_facet | Amen, Yhiya Elsbaey, Marwa Othman, Ahmed Sallam, Mahmoud Shimizu, Kuniyoshi |
author_sort | Amen, Yhiya |
collection | PubMed |
description | Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti-inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone glycosides, suggesting their potential as drug leads. This review compiles 192 naturally occurring chromone glycosides along with their sources, classification, biological activities, and spectroscopic features. Detailed biosynthetic pathways and chemotaxonomic studies are also described. Extensive spectroscopic features for this class of compounds have been thoroughly discussed, and detailed (13)C-NMR data of compounds 1–192, have been added, except for those that have no reported (13)C-NMR data. |
format | Online Article Text |
id | pubmed-8704703 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87047032021-12-25 Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features Amen, Yhiya Elsbaey, Marwa Othman, Ahmed Sallam, Mahmoud Shimizu, Kuniyoshi Molecules Review Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti-inflammatory, antitumor, antimicrobial, etc., have been discovered for chromone glycosides, suggesting their potential as drug leads. This review compiles 192 naturally occurring chromone glycosides along with their sources, classification, biological activities, and spectroscopic features. Detailed biosynthetic pathways and chemotaxonomic studies are also described. Extensive spectroscopic features for this class of compounds have been thoroughly discussed, and detailed (13)C-NMR data of compounds 1–192, have been added, except for those that have no reported (13)C-NMR data. MDPI 2021-12-16 /pmc/articles/PMC8704703/ /pubmed/34946728 http://dx.doi.org/10.3390/molecules26247646 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Amen, Yhiya Elsbaey, Marwa Othman, Ahmed Sallam, Mahmoud Shimizu, Kuniyoshi Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features |
title | Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features |
title_full | Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features |
title_fullStr | Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features |
title_full_unstemmed | Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features |
title_short | Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features |
title_sort | naturally occurring chromone glycosides: sources, bioactivities, and spectroscopic features |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704703/ https://www.ncbi.nlm.nih.gov/pubmed/34946728 http://dx.doi.org/10.3390/molecules26247646 |
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