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Improved Anticancer Activities of a New Pentafluorothio-Substituted Vorinostat-Type Histone Deacetylase Inhibitor

The development of new anticancer drugs is necessary in order deal with the disease and with the drawbacks of currently applied drugs. Epigenetic dysregulations are a central hallmark of cancerogenesis and histone deacetylases (HDACs) emerged as promising anticancer targets. HDAC inhibitors are prom...

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Detalles Bibliográficos
Autores principales:	Goehringer, Nils, Peng, Yayi, Nitzsche, Bianca, Biermann, Hannah, Pradhan, Rohan, Schobert, Rainer, Herling, Marco, Höpfner, Michael, Biersack, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704709/ https://www.ncbi.nlm.nih.gov/pubmed/34959719 http://dx.doi.org/10.3390/ph14121319

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