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Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points
(1) Background: Since 2015, exception points have been awarded to appropriate candidates after six months of waitlist time to allow more equitable access to liver transplants regardless of hepatocellular carcinoma status. However, it remains unknown whether racial disparities in outcomes among waitl...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704844/ https://www.ncbi.nlm.nih.gov/pubmed/34945122 http://dx.doi.org/10.3390/jcm10245826 |
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author | Goyes, Daniela Nsubuga, John Paul Medina-Morales, Esli Barba, Romelia Patwardhan, Vilas Saberi, Behnam Fricker, Zachary Bonder, Alan |
author_facet | Goyes, Daniela Nsubuga, John Paul Medina-Morales, Esli Barba, Romelia Patwardhan, Vilas Saberi, Behnam Fricker, Zachary Bonder, Alan |
author_sort | Goyes, Daniela |
collection | PubMed |
description | (1) Background: Since 2015, exception points have been awarded to appropriate candidates after six months of waitlist time to allow more equitable access to liver transplants regardless of hepatocellular carcinoma status. However, it remains unknown whether racial disparities in outcomes among waitlisted patients remain after the introduction of a 6-month waiting period for exception points. (2) Methods: Using the United Network for Organ Sharing database, we identified 2311 patients diagnosed with hepatocellular carcinoma listed for liver transplant who received exception points from 2015 to 2019. The outcome of interest was waitlist survival defined as the composite outcome of death or removal for clinical deterioration. Competing risk analysis was used to identify factors associated with death or removal for clinical deterioration. The final model adjusted for age, sex, race/ethnicity, blood type, diabetes, obesity, laboratory MELD score, tumor size, AFP, locoregional therapies, UNOS region, and college education. (3) Results: No difference was found in the risk of adverse waitlist removal among ethnic/racial groups. |
format | Online Article Text |
id | pubmed-8704844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87048442021-12-25 Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points Goyes, Daniela Nsubuga, John Paul Medina-Morales, Esli Barba, Romelia Patwardhan, Vilas Saberi, Behnam Fricker, Zachary Bonder, Alan J Clin Med Article (1) Background: Since 2015, exception points have been awarded to appropriate candidates after six months of waitlist time to allow more equitable access to liver transplants regardless of hepatocellular carcinoma status. However, it remains unknown whether racial disparities in outcomes among waitlisted patients remain after the introduction of a 6-month waiting period for exception points. (2) Methods: Using the United Network for Organ Sharing database, we identified 2311 patients diagnosed with hepatocellular carcinoma listed for liver transplant who received exception points from 2015 to 2019. The outcome of interest was waitlist survival defined as the composite outcome of death or removal for clinical deterioration. Competing risk analysis was used to identify factors associated with death or removal for clinical deterioration. The final model adjusted for age, sex, race/ethnicity, blood type, diabetes, obesity, laboratory MELD score, tumor size, AFP, locoregional therapies, UNOS region, and college education. (3) Results: No difference was found in the risk of adverse waitlist removal among ethnic/racial groups. MDPI 2021-12-13 /pmc/articles/PMC8704844/ /pubmed/34945122 http://dx.doi.org/10.3390/jcm10245826 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Goyes, Daniela Nsubuga, John Paul Medina-Morales, Esli Barba, Romelia Patwardhan, Vilas Saberi, Behnam Fricker, Zachary Bonder, Alan Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points |
title | Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points |
title_full | Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points |
title_fullStr | Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points |
title_full_unstemmed | Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points |
title_short | Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points |
title_sort | race/ethnicity is not independently associated with risk of adverse waitlist removal among patients with hcc exception points |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704844/ https://www.ncbi.nlm.nih.gov/pubmed/34945122 http://dx.doi.org/10.3390/jcm10245826 |
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