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Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points

(1) Background: Since 2015, exception points have been awarded to appropriate candidates after six months of waitlist time to allow more equitable access to liver transplants regardless of hepatocellular carcinoma status. However, it remains unknown whether racial disparities in outcomes among waitl...

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Autores principales: Goyes, Daniela, Nsubuga, John Paul, Medina-Morales, Esli, Barba, Romelia, Patwardhan, Vilas, Saberi, Behnam, Fricker, Zachary, Bonder, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704844/
https://www.ncbi.nlm.nih.gov/pubmed/34945122
http://dx.doi.org/10.3390/jcm10245826
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author Goyes, Daniela
Nsubuga, John Paul
Medina-Morales, Esli
Barba, Romelia
Patwardhan, Vilas
Saberi, Behnam
Fricker, Zachary
Bonder, Alan
author_facet Goyes, Daniela
Nsubuga, John Paul
Medina-Morales, Esli
Barba, Romelia
Patwardhan, Vilas
Saberi, Behnam
Fricker, Zachary
Bonder, Alan
author_sort Goyes, Daniela
collection PubMed
description (1) Background: Since 2015, exception points have been awarded to appropriate candidates after six months of waitlist time to allow more equitable access to liver transplants regardless of hepatocellular carcinoma status. However, it remains unknown whether racial disparities in outcomes among waitlisted patients remain after the introduction of a 6-month waiting period for exception points. (2) Methods: Using the United Network for Organ Sharing database, we identified 2311 patients diagnosed with hepatocellular carcinoma listed for liver transplant who received exception points from 2015 to 2019. The outcome of interest was waitlist survival defined as the composite outcome of death or removal for clinical deterioration. Competing risk analysis was used to identify factors associated with death or removal for clinical deterioration. The final model adjusted for age, sex, race/ethnicity, blood type, diabetes, obesity, laboratory MELD score, tumor size, AFP, locoregional therapies, UNOS region, and college education. (3) Results: No difference was found in the risk of adverse waitlist removal among ethnic/racial groups.
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spelling pubmed-87048442021-12-25 Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points Goyes, Daniela Nsubuga, John Paul Medina-Morales, Esli Barba, Romelia Patwardhan, Vilas Saberi, Behnam Fricker, Zachary Bonder, Alan J Clin Med Article (1) Background: Since 2015, exception points have been awarded to appropriate candidates after six months of waitlist time to allow more equitable access to liver transplants regardless of hepatocellular carcinoma status. However, it remains unknown whether racial disparities in outcomes among waitlisted patients remain after the introduction of a 6-month waiting period for exception points. (2) Methods: Using the United Network for Organ Sharing database, we identified 2311 patients diagnosed with hepatocellular carcinoma listed for liver transplant who received exception points from 2015 to 2019. The outcome of interest was waitlist survival defined as the composite outcome of death or removal for clinical deterioration. Competing risk analysis was used to identify factors associated with death or removal for clinical deterioration. The final model adjusted for age, sex, race/ethnicity, blood type, diabetes, obesity, laboratory MELD score, tumor size, AFP, locoregional therapies, UNOS region, and college education. (3) Results: No difference was found in the risk of adverse waitlist removal among ethnic/racial groups. MDPI 2021-12-13 /pmc/articles/PMC8704844/ /pubmed/34945122 http://dx.doi.org/10.3390/jcm10245826 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Goyes, Daniela
Nsubuga, John Paul
Medina-Morales, Esli
Barba, Romelia
Patwardhan, Vilas
Saberi, Behnam
Fricker, Zachary
Bonder, Alan
Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points
title Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points
title_full Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points
title_fullStr Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points
title_full_unstemmed Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points
title_short Race/Ethnicity Is Not Independently Associated with Risk of Adverse Waitlist Removal among Patients with HCC Exception Points
title_sort race/ethnicity is not independently associated with risk of adverse waitlist removal among patients with hcc exception points
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704844/
https://www.ncbi.nlm.nih.gov/pubmed/34945122
http://dx.doi.org/10.3390/jcm10245826
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