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Visfatin and Resveratrol Differentially Regulate the Expression of Thymidylate Synthase to Control the Sensitivity of Human Colorectal Cancer Cells to Capecitabine Cytotoxicity

Colorectal cancer (CRC) is a highly lethal malignant cancer. Capecitabine, a 5-fluororacil (5-FU) derivate, is its first-line drug, but the resistance of CRC to capecitabine is still the most challenging factor for curing patients. It has been suggested that thymidylate synthase (TYMS) level might a...

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Detalles Bibliográficos
Autores principales: Wu, Kuen-Lin, Lee, Ko-Chao, Yen, Chia-Kuang, Chen, Cheng-Nan, Chang, Shun-Fu, Huang, Wen-Shih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704879/
https://www.ncbi.nlm.nih.gov/pubmed/34947902
http://dx.doi.org/10.3390/life11121371