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From Far West to East: Joining the Molecular Architecture of Imidazole-like Ligands in HO-1 Complexes

HO-1 overexpression has been reported in several cases/types of human malignancies. Unfortunately, poor clinical outcomes are reported in most of these cases, and the inhibition of HO-1 is considered a valuable and proven anticancer approach. To identify novel hit compounds suitable as HO-1 inhibito...

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Detalles Bibliográficos
Autores principales: Floresta, Giuseppe, Fallica, Antonino Nicolò, Patamia, Vincenzo, Sorrenti, Valeria, Greish, Khaled, Rescifina, Antonio, Pittalà, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704944/
https://www.ncbi.nlm.nih.gov/pubmed/34959690
http://dx.doi.org/10.3390/ph14121289