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Transient CRISPR-Cas Treatment Can Prevent Reactivation of HIV-1 Replication in a Latently Infected T-Cell Line

Novel therapeutic strategies aiming at the permanent inactivation of the HIV-1 reservoir in infected individuals are currently being explored, including approaches based on CRISPR-Cas gene editing. Extinction of all infectious HIV provirus in infected T-cell cultures was previously achieved when cel...

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Detalles Bibliográficos
Autores principales:	Liu, Ye, Jeeninga, Rienk E., Klaver, Bep, Berkhout, Ben, Das, Atze T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705111/ https://www.ncbi.nlm.nih.gov/pubmed/34960730 http://dx.doi.org/10.3390/v13122461

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