Intravenous tacrolimus is a superior induction therapy for acute severe ulcerative colitis compared to oral tacrolimus

BACKGROUND: Intravenous corticosteroid is the mainstay for managing acute severe ulcerative colitis, but one-third of patients do not respond to intravenous corticosteroid. Tacrolimus, a salvage therapy before colectomy, is usually orally administered, though its bioavailability is low compared intr...

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Detalles Bibliográficos
Autores principales: Shimizu, Hiromichi, Fujii, Toshimitsu, Kinoshita, Kenji, Kawamoto, Ami, Hibiya, Shuji, Takenaka, Kento, Saito, Eiko, Nagahori, Masakazu, Ohtsuka, Kazuo, Watanabe, Mamoru, Okamoto, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705155/
https://www.ncbi.nlm.nih.gov/pubmed/34949172
http://dx.doi.org/10.1186/s12876-021-02043-6

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