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Spleen tyrosine kinase facilitates neutrophil activation and worsens long-term neurologic deficits after spinal cord injury

BACKGROUND: Spinal cord injury elicits widespread inflammation that can exacerbate long-term neurologic deficits. Neutrophils are the most abundant immune cell type to invade the spinal cord in the early acute phase after injury, however, their role in secondary pathogenesis and functional recovery...

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Detalles Bibliográficos
Autores principales: McCreedy, Dylan A., Abram, Clare L., Hu, Yongmei, Min, Sun Won, Platt, Madison E., Kirchhoff, Megan A., Reid, Shelby K., Jalufka, Frank L., Lowell, Clifford A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705173/
https://www.ncbi.nlm.nih.gov/pubmed/34952603
http://dx.doi.org/10.1186/s12974-021-02353-2