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Spleen tyrosine kinase facilitates neutrophil activation and worsens long-term neurologic deficits after spinal cord injury
BACKGROUND: Spinal cord injury elicits widespread inflammation that can exacerbate long-term neurologic deficits. Neutrophils are the most abundant immune cell type to invade the spinal cord in the early acute phase after injury, however, their role in secondary pathogenesis and functional recovery...
Autores principales: | McCreedy, Dylan A., Abram, Clare L., Hu, Yongmei, Min, Sun Won, Platt, Madison E., Kirchhoff, Megan A., Reid, Shelby K., Jalufka, Frank L., Lowell, Clifford A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705173/ https://www.ncbi.nlm.nih.gov/pubmed/34952603 http://dx.doi.org/10.1186/s12974-021-02353-2 |
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