Cargando…

Camptothecin Encapsulated in β-Cyclodextrin-EDTA-Fe(3)O(4) Nanoparticles Induce Metabolic Reprogramming Repair in HT29 Cancer Cells through Epigenetic Modulation: A Bioinformatics Approach

Cancer progresses through a distinctive reprogramming of metabolic pathways directed by genetic and epigenetic modifications. The hardwired changes induced by genetic mutations are resilient, while epigenetic modifications are softwired and more vulnerable to therapeutic intervention. Colon cancer i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Farhana, Aisha, Koh, Avin Ee-Hwan, Ling Mok, Pooi, Alsrhani, Abdullah, Khan, Yusuf Saleem, Subbiah, Suresh Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705212/ https://www.ncbi.nlm.nih.gov/pubmed/34947512 http://dx.doi.org/10.3390/nano11123163

Ejemplares similares

Treatment of HT29 Human Colorectal Cancer Cell Line with Nanocarrier-Encapsulated Camptothecin Reveals Histone Modifier Genes in the Wnt Signaling Pathway as Important Molecular Cues for Colon Cancer Targeting
por: Farhana, Aisha, et al.
Publicado: (2021)

Nanoparticle-Encapsulated Camptothecin: Epigenetic Modulation in DNA Repair Mechanisms in Colon Cancer Cells
por: Farhana, Aisha, et al.
Publicado: (2021)

Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe(3)O(4) nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug
por: Krishnan, Poorani, et al.
Publicado: (2017)

Computational drug screening against the SARS-CoV-2 Saudi Arabia isolates through a multiple-sequence alignment approach
por: Mok, Pooi Ling, et al.
Publicado: (2021)

In silico Prediction of Deleterious Single Nucleotide Polymorphism in S100A4 Metastatic Gene: Potential Early Diagnostic Marker
por: Farhana, Aisha, et al.
Publicado: (2022)

Mitigation of Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells in vitro by Transgenic Erythropoietin-Expressing Mesenchymal Stem Cells
por: Koh, Avin Ee-Hwan, et al.
Publicado: (2021)

Corrigendum: Mitigation of Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells in vitro by Transgenic Erythropoietin-Expressing Mesenchymal Stem Cells
por: Koh, Avin Ee-Hwan, et al.
Publicado: (2021)

Cancer Bioenergetics and Tumor Microenvironments—Enhancing Chemotherapeutics and Targeting Resistant Niches through Nanosystems
por: Farhana, Aisha, et al.
Publicado: (2023)

Therapeutic Potential of Albumin Nanoparticles Encapsulated Visnagin in MDA-MB-468 Triple-Negative Breast Cancer Cells
por: Alsrhani, Abdullah, et al.
Publicado: (2023)

Gold Nanoparticles Inhibit PMA-Induced MMP-9 Expression via microRNA-204-5p Upregulation and Deactivation of NF-κBp65 in Breast Cancer Cells
por: Farhana, Aisha, et al.
Publicado: (2023)

Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers
por: Chen, Yi-Fan, et al.
Publicado: (2019)

Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma
por: Mok, Pooi Ling, et al.
Publicado: (2021)

Empowering Mesenchymal Stem Cells for Ocular Degenerative Disorders
por: Ding, Shirley Suet Lee, et al.
Publicado: (2019)

Formation of nanoparticles by cooperative inclusion between (S)-camptothecin-modified dextrans and β-cyclodextrin polymers
por: Nielsen, Thorbjørn Terndrup, et al.
Publicado: (2015)

Hypoxia in Bone and Oxygen Releasing Biomaterials in Fracture Treatments Using Mesenchymal Stem Cell Therapy: A Review
por: Teh, Seoh Wei, et al.
Publicado: (2021)

Anticancer effect of dentatin and dentatin-hydroxypropyl-β-cyclodextrin complex on human colon cancer (HT-29) cell line
por: AL-Abboodi, Ashwaq Shakir, et al.
Publicado: (2017)

Formulation development, stability and anticancer efficacy of core-shell cyclodextrin nanocapsules for oral chemotherapy with camptothecin
por: Ünal, Hale, et al.
Publicado: (2015)

Combined In Silico and Experimental Investigations of Resveratrol Encapsulation by Beta-Cyclodextrin
por: Iskineyeva, Ainara, et al.
Publicado: (2022)

Gold nanoparticles attenuate the interferon-γ induced SOCS1 expression and activation of NF-κB p65/50 activity via modulation of microRNA-155-5p in triple-negative breast cancer cells
por: Farhana, Aisha, et al.
Publicado: (2023)

Corrigendum: Transplanted Erythropoietin-Expressing Mesenchymal Stem Cells Promote Pro-survival Gene Expression and Protect Photoreceptors From Sodium Iodate-Induced Cytotoxicity in a Retinal Degeneration Model
por: Koh, Avin Ee-Hwan, et al.
Publicado: (2021)

Transplanted Erythropoietin-Expressing Mesenchymal Stem Cells Promote Pro-survival Gene Expression and Protect Photoreceptors From Sodium Iodate-Induced Cytotoxicity in a Retinal Degeneration Model
por: Koh, Avin Ee-Hwan, et al.
Publicado: (2021)

Combined Computational and Experimental Studies of Anabasine Encapsulation by Beta-Cyclodextrin
por: Muldakhmetov, Zeinolla, et al.
Publicado: (2022)

Exploring the Influence of Spacers in EDTA–β-Cyclodextrin Dendrimers: Physicochemical Properties and In Vitro Biological Behavior
por: González-Méndez, Israel, et al.
Publicado: (2023)

Encapsulation Mechanism of Oxyresveratrol by β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin and Computational Analysis
por: He, Jianfei, et al.
Publicado: (2017)

Anti-tumor activity of N-trimethyl chitosan-encapsulated camptothecin in a mouse melanoma model
por: Liu, Xian-ping, et al.
Publicado: (2010)

Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles
por: Prandina, Anthony, et al.
Publicado: (2018)

Cyclodextrin modified niosomes to encapsulate hydrophilic compounds
por: Machado, Noelia D., et al.
Publicado: (2018)

Encapsulation mechanism of α-mangostin by β-cyclodextrin: Methods of molecular docking and molecular dynamics
por: Triwahyuningtyas, Dian, et al.
Publicado: (2021)

One-pot synthesis of trifunctional chitosan-EDTA-β-cyclodextrin polymer for simultaneous removal of metals and organic micropollutants
por: Zhao, Feiping, et al.
Publicado: (2017)

Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene
por: Liu, Yamin, et al.
Publicado: (2017)

The impact of camptothecin-encapsulated poly(lactic-co-glycolic acid) nanoparticles on the activity of cytochrome P450 in vitro
por: Bao, Hanmei, et al.
Publicado: (2019)

Sorting of sphingolipids in the endocytic pathway of HT29 cells
Publicado: (1991)

Synthesis of β-Cyclodextrin-Decorated Dendritic Compounds Based on EDTA Core: A New Class of PAMAM Dendrimer Analogs
por: González-Méndez, Israel, et al.
Publicado: (2022)

Effects of Albumin–Chlorogenic Acid Nanoparticles on Apoptosis and PI3K/Akt/mTOR Pathway Inhibitory Activity in MDA-MB-435s Cells
por: Alzahrani, Badr, et al.
Publicado: (2023)

Encapsulation of biocides by cyclodextrins: toward synergistic effects against pathogens
por: Nardello-Rataj, Véronique, et al.
Publicado: (2014)

Encapsulation of α-Pinene in Delivery Systems Based on Liposomes and Cyclodextrins
por: Hammoud, Zahraa, et al.
Publicado: (2021)

A Review of Cyclodextrin Encapsulation and Intelligent Response for the Release of Curcumin
por: Li, Jing, et al.
Publicado: (2022)

Targeted Fisetin-Encapsulated β-Cyclodextrin Nanosponges for Breast Cancer
por: Aboushanab, Alaa R., et al.
Publicado: (2023)

Effects of the combination of camptothecin and doxorubicin or etoposide on rat glioma cells and camptothecin-resistant variants
por: Pavillard, V, et al.
Publicado: (2001)

Characterization of DNA Topoisomerase-1 in Spodoptera exigua for Toxicity Evaluation of Camptothecin and Hydoxy-Camptothecin
por: Zhang, Lan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_6dmrmkco80pupnoab8nhoeech3