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High-Resolution Scanning Coded-Mask-Based X-ray Multi-Contrast Imaging and Tomography

Near-field X-ray speckle tracking has been used in phase-contrast imaging and tomography as an emerging technique, providing higher contrast images than traditional absorption radiography. Most reported methods use sandpaper or membrane filters as speckle generators and digital image cross-correlati...

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Detalles Bibliográficos
Autores principales: Qiao, Zhi, Shi, Xianbo, Wojcik, Michael, Assoufid, Lahsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705295/
https://www.ncbi.nlm.nih.gov/pubmed/34940716
http://dx.doi.org/10.3390/jimaging7120249
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author Qiao, Zhi
Shi, Xianbo
Wojcik, Michael
Assoufid, Lahsen
author_facet Qiao, Zhi
Shi, Xianbo
Wojcik, Michael
Assoufid, Lahsen
author_sort Qiao, Zhi
collection PubMed
description Near-field X-ray speckle tracking has been used in phase-contrast imaging and tomography as an emerging technique, providing higher contrast images than traditional absorption radiography. Most reported methods use sandpaper or membrane filters as speckle generators and digital image cross-correlation for phase reconstruction, which has either limited resolution or requires a large number of position scanning steps. Recently, we have proposed a novel coded-mask-based multi-contrast imaging (CMMI) technique for single-shot measurement with superior performance in efficiency and resolution compared with other single-shot methods. We present here a scanning CMMI method for the ultimate imaging resolution and phase sensitivity by using a coded mask as a high-contrast speckle generator, the flexible scanning mode, the adaption of advanced maximum-likelihood optimization to scanning data, and the multi-resolution analysis. Scanning CMMI can outperform other speckle-based imaging methods, such as X-ray speckle vector tracking, providing higher quality absorption, phase, and dark-field images with fewer scanning steps. Scanning CMMI is also successfully demonstrated in multi-contrast tomography, showing great potentials in high-resolution full-field imaging applications, such as in vivo biomedical imaging.
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spelling pubmed-87052952021-12-25 High-Resolution Scanning Coded-Mask-Based X-ray Multi-Contrast Imaging and Tomography Qiao, Zhi Shi, Xianbo Wojcik, Michael Assoufid, Lahsen J Imaging Article Near-field X-ray speckle tracking has been used in phase-contrast imaging and tomography as an emerging technique, providing higher contrast images than traditional absorption radiography. Most reported methods use sandpaper or membrane filters as speckle generators and digital image cross-correlation for phase reconstruction, which has either limited resolution or requires a large number of position scanning steps. Recently, we have proposed a novel coded-mask-based multi-contrast imaging (CMMI) technique for single-shot measurement with superior performance in efficiency and resolution compared with other single-shot methods. We present here a scanning CMMI method for the ultimate imaging resolution and phase sensitivity by using a coded mask as a high-contrast speckle generator, the flexible scanning mode, the adaption of advanced maximum-likelihood optimization to scanning data, and the multi-resolution analysis. Scanning CMMI can outperform other speckle-based imaging methods, such as X-ray speckle vector tracking, providing higher quality absorption, phase, and dark-field images with fewer scanning steps. Scanning CMMI is also successfully demonstrated in multi-contrast tomography, showing great potentials in high-resolution full-field imaging applications, such as in vivo biomedical imaging. MDPI 2021-11-24 /pmc/articles/PMC8705295/ /pubmed/34940716 http://dx.doi.org/10.3390/jimaging7120249 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Qiao, Zhi
Shi, Xianbo
Wojcik, Michael
Assoufid, Lahsen
High-Resolution Scanning Coded-Mask-Based X-ray Multi-Contrast Imaging and Tomography
title High-Resolution Scanning Coded-Mask-Based X-ray Multi-Contrast Imaging and Tomography
title_full High-Resolution Scanning Coded-Mask-Based X-ray Multi-Contrast Imaging and Tomography
title_fullStr High-Resolution Scanning Coded-Mask-Based X-ray Multi-Contrast Imaging and Tomography
title_full_unstemmed High-Resolution Scanning Coded-Mask-Based X-ray Multi-Contrast Imaging and Tomography
title_short High-Resolution Scanning Coded-Mask-Based X-ray Multi-Contrast Imaging and Tomography
title_sort high-resolution scanning coded-mask-based x-ray multi-contrast imaging and tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705295/
https://www.ncbi.nlm.nih.gov/pubmed/34940716
http://dx.doi.org/10.3390/jimaging7120249
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