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Nanomaterials: Synthesis and Applications in Theranostics

Nanomaterials are endowed with unique features and essential properties suitable for employing in the field of nanomedicine. The nanomaterials can be classified as 0D, 1D, 2D, and 3D based on their dimensions. The nanomaterials can be malleable and ductile and they can be drawn into wires and sheets...

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Autores principales: Paramasivam, Gokul, Palem, Vishnu Vardhan, Sundaram, Thanigaivel, Sundaram, Vickram, Kishore, Somasundaram Chandra, Bellucci, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705396/
https://www.ncbi.nlm.nih.gov/pubmed/34947577
http://dx.doi.org/10.3390/nano11123228
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author Paramasivam, Gokul
Palem, Vishnu Vardhan
Sundaram, Thanigaivel
Sundaram, Vickram
Kishore, Somasundaram Chandra
Bellucci, Stefano
author_facet Paramasivam, Gokul
Palem, Vishnu Vardhan
Sundaram, Thanigaivel
Sundaram, Vickram
Kishore, Somasundaram Chandra
Bellucci, Stefano
author_sort Paramasivam, Gokul
collection PubMed
description Nanomaterials are endowed with unique features and essential properties suitable for employing in the field of nanomedicine. The nanomaterials can be classified as 0D, 1D, 2D, and 3D based on their dimensions. The nanomaterials can be malleable and ductile and they can be drawn into wires and sheets. Examples of nanomaterials are quantum dots (0D), nanorods, nanowires (1D), nanosheets (2D), and nanocubes (3D). These nanomaterials can be synthesized using top-down and bottom-up approaches. The achievements of 0D and 1D nanomaterials are used to detect trace heavy metal (e.g., Pb(2+)) and have higher sensitivity with the order of five as compared to conventional sensors. The achievements of 2D and 3D nanomaterials are used as diagnostic and therapeutic agents with multifunctional ability in imaging systems such as PET, SPECT, etc. These imaging modalities can be used to track the drug in living tissues. This review comprises the state-of-the-art of the different dimensions of the nanomaterials employed in theranostics. The nanomaterials with different dimensions have unique physicochemical properties that can be utilized for therapy and diagnosis. The multifunctional ability of the nanomaterials can have a distinct advantage that is used in the field of theranostics. Different dimensions of the nanomaterials would have more scope in the field of nanomedicine.
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spelling pubmed-87053962021-12-25 Nanomaterials: Synthesis and Applications in Theranostics Paramasivam, Gokul Palem, Vishnu Vardhan Sundaram, Thanigaivel Sundaram, Vickram Kishore, Somasundaram Chandra Bellucci, Stefano Nanomaterials (Basel) Review Nanomaterials are endowed with unique features and essential properties suitable for employing in the field of nanomedicine. The nanomaterials can be classified as 0D, 1D, 2D, and 3D based on their dimensions. The nanomaterials can be malleable and ductile and they can be drawn into wires and sheets. Examples of nanomaterials are quantum dots (0D), nanorods, nanowires (1D), nanosheets (2D), and nanocubes (3D). These nanomaterials can be synthesized using top-down and bottom-up approaches. The achievements of 0D and 1D nanomaterials are used to detect trace heavy metal (e.g., Pb(2+)) and have higher sensitivity with the order of five as compared to conventional sensors. The achievements of 2D and 3D nanomaterials are used as diagnostic and therapeutic agents with multifunctional ability in imaging systems such as PET, SPECT, etc. These imaging modalities can be used to track the drug in living tissues. This review comprises the state-of-the-art of the different dimensions of the nanomaterials employed in theranostics. The nanomaterials with different dimensions have unique physicochemical properties that can be utilized for therapy and diagnosis. The multifunctional ability of the nanomaterials can have a distinct advantage that is used in the field of theranostics. Different dimensions of the nanomaterials would have more scope in the field of nanomedicine. MDPI 2021-11-28 /pmc/articles/PMC8705396/ /pubmed/34947577 http://dx.doi.org/10.3390/nano11123228 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Paramasivam, Gokul
Palem, Vishnu Vardhan
Sundaram, Thanigaivel
Sundaram, Vickram
Kishore, Somasundaram Chandra
Bellucci, Stefano
Nanomaterials: Synthesis and Applications in Theranostics
title Nanomaterials: Synthesis and Applications in Theranostics
title_full Nanomaterials: Synthesis and Applications in Theranostics
title_fullStr Nanomaterials: Synthesis and Applications in Theranostics
title_full_unstemmed Nanomaterials: Synthesis and Applications in Theranostics
title_short Nanomaterials: Synthesis and Applications in Theranostics
title_sort nanomaterials: synthesis and applications in theranostics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705396/
https://www.ncbi.nlm.nih.gov/pubmed/34947577
http://dx.doi.org/10.3390/nano11123228
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