Semi-Quantitative Multiplex Profiling of the Complement System Identifies Associations of Complement Proteins with Genetic Variants and Metabolites in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a major cause of vision loss among the elderly in the Western world. The complement system has been identified as one of the main AMD disease pathways. We performed a comprehensive expression analysis of 32 complement proteins in plasma samples of 255 AMD pa...

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Detalles Bibliográficos
Autores principales: Acar, I. Erkin, Willems, Esther, Kersten, Eveline, Keizer-Garritsen, Jenneke, Kragt, Else, Bakker, Bjorn, Galesloot, Tessel E., Hoyng, Carel B., Fauser, Sascha, van Gool, Alain J., Lechanteur, Yara T. E., Koertvely, Elod, Nogoceke, Everson, Gloerich, Jolein, de Jonge, Marien I., Lorés-Motta, Laura, den Hollander, Anneke I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705464/
https://www.ncbi.nlm.nih.gov/pubmed/34945728
http://dx.doi.org/10.3390/jpm11121256

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