Optimizing Solvent Selection and Processing Conditions to Generate High Bulk-Density, Co-Precipitated Amorphous Dispersions of Posaconazole

Co-precipitation is an emerging method to generate amorphous solid dispersions (ASDs), notable for its ability to enable the production of ASDs containing pharmaceuticals with thermal instability and limited solubility. As is true for spray drying and other unit operations to generate amorphous mate...

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Detalles Bibliográficos
Autores principales: Frank, Derek, Schenck, Luke, Koynov, Athanas, Su, Yongchao, Li, Yongjun, Variankaval, Narayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705469/
https://www.ncbi.nlm.nih.gov/pubmed/34959298
http://dx.doi.org/10.3390/pharmaceutics13122017

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