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Diet and Dementia: A Prospective Study

Whether dietary and nutrition and dietary patterns are associated with the development of dementia is an interesting research question. Participants of a longitudinal cohort study that included European adults who were middle to old aged at baseline and who had not been diagnosed with dementia at ba...

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Autores principales: Takeuchi, Hikaru, Kawashima, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705494/
https://www.ncbi.nlm.nih.gov/pubmed/34960052
http://dx.doi.org/10.3390/nu13124500
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author Takeuchi, Hikaru
Kawashima, Ryuta
author_facet Takeuchi, Hikaru
Kawashima, Ryuta
author_sort Takeuchi, Hikaru
collection PubMed
description Whether dietary and nutrition and dietary patterns are associated with the development of dementia is an interesting research question. Participants of a longitudinal cohort study that included European adults who were middle to old aged at baseline and who had not been diagnosed with dementia at baseline (2006–2010) and had not been diagnosed with dementia or died within 5 years after baseline were followed up (until 2018) and analyzed. Associations between intake frequency of each food class measured by the food-frequency questionnaire at baseline and incident dementia 5 years after baseline were analyzed after correcting for confounding variables. A total of approximately 340,000 participants and 900 cases were included in the analysis for each food class. Cox proportional hazard models with self-reported intake level of each food category divided into four mostly equally divided categorical variables revealed a high intake of bread, moderate total meat and total fish intake and low vegetable and fruit intake were thus associated with a small but significant decrease in the onset risk of dementia, while poultry and cereal were not. These findings are mostly inconsistent with the idea that Mediterranean diet is associated with lower risk of subsequent incident dementia.
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spelling pubmed-87054942021-12-25 Diet and Dementia: A Prospective Study Takeuchi, Hikaru Kawashima, Ryuta Nutrients Article Whether dietary and nutrition and dietary patterns are associated with the development of dementia is an interesting research question. Participants of a longitudinal cohort study that included European adults who were middle to old aged at baseline and who had not been diagnosed with dementia at baseline (2006–2010) and had not been diagnosed with dementia or died within 5 years after baseline were followed up (until 2018) and analyzed. Associations between intake frequency of each food class measured by the food-frequency questionnaire at baseline and incident dementia 5 years after baseline were analyzed after correcting for confounding variables. A total of approximately 340,000 participants and 900 cases were included in the analysis for each food class. Cox proportional hazard models with self-reported intake level of each food category divided into four mostly equally divided categorical variables revealed a high intake of bread, moderate total meat and total fish intake and low vegetable and fruit intake were thus associated with a small but significant decrease in the onset risk of dementia, while poultry and cereal were not. These findings are mostly inconsistent with the idea that Mediterranean diet is associated with lower risk of subsequent incident dementia. MDPI 2021-12-16 /pmc/articles/PMC8705494/ /pubmed/34960052 http://dx.doi.org/10.3390/nu13124500 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Takeuchi, Hikaru
Kawashima, Ryuta
Diet and Dementia: A Prospective Study
title Diet and Dementia: A Prospective Study
title_full Diet and Dementia: A Prospective Study
title_fullStr Diet and Dementia: A Prospective Study
title_full_unstemmed Diet and Dementia: A Prospective Study
title_short Diet and Dementia: A Prospective Study
title_sort diet and dementia: a prospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705494/
https://www.ncbi.nlm.nih.gov/pubmed/34960052
http://dx.doi.org/10.3390/nu13124500
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