Dose Finding and Food Effect Studies of a Novel Abiraterone Acetate Formulation for Oral Suspension in Comparison to a Reference Formulation in Healthy Male Subjects

Currently approved formulations of the androgen synthesis inhibitor abiraterone acetate (AA) consist of multiple tablets administered daily in a fasted state. Removing the food effect and switching to a suspension formulation is expected to improve the pharmacokinetic profile and facilitate drug adm...

Descripción completa

Detalles Bibliográficos
Autores principales: Jordán, Tamás, Basa-Dénes, Orsolya, Angi, Réka, Orosz, János, Ötvös, Zsolt, Ujhelyi, Andrea, Filipcsei, Genovéva, Molnár, László, Solymosi, Tamás, Glavinas, Hristos, Capone, Dominic, Whitfield, Nicola, McDermott, John, McKenzie, Litza, Shurety, Lauren, Duus, Elizabeth Manning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705659/
https://www.ncbi.nlm.nih.gov/pubmed/34959452
http://dx.doi.org/10.3390/pharmaceutics13122171

Ejemplares similares

Ejemplares similares