Cargando…

The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative

Acridine cell-penetrating peptide conjugates are an extremely important family of compounds in antitumor chemotherapy. These conjugates are not so widely analysed in antimicrobial therapy, although bioactive peptides could be used as nanocarriers to smuggle antimicrobial compounds. An octaarginine c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rząd, Kamila, Paluszkiewicz, Ewa, Neubauer, Damian, Olszewski, Mateusz, Kozłowska-Tylingo, Katarzyna, Kamysz, Wojciech, Gabriel, Iwona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705783/ https://www.ncbi.nlm.nih.gov/pubmed/34947987 http://dx.doi.org/10.3390/ijms222413190

Ejemplares similares

Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity
por: Gabriel, Iwona, et al.
Publicado: (2021)

Enhancing Aqueous Solubility and Antibacterial Activity of Curcumin by Complexing with Cell-Penetrating Octaarginine
por: Ratrey, Poonam, et al.
Publicado: (2020)

Emergent antibacterial activity of N-(thiazol-2-yl)benzenesulfonamides in conjunction with cell-penetrating octaarginine
por: Ratrey, Poonam, et al.
Publicado: (2021)

Cooperative Cellular Uptake and Activity of Octaarginine Antisense Peptide Nucleic Acid (PNA) Conjugates
por: Ghavami, Mahdi, et al.
Publicado: (2019)

Antifungal Effect of Penicillamine Due to the Selective Targeting of L-Homoserine O-Acetyltransferase
por: Kuplińska, Aleksandra, et al.
Publicado: (2022)

Quest for the Molecular Basis of Improved Selective Toxicity of All-Trans Isomers of Aromatic Heptaene Macrolide Antifungal Antibiotics
por: Borzyszkowska-Bukowska, Julia, et al.
Publicado: (2021)

Octaarginine Improves the Efficacy of Nitazoxanide against Cryptosporidium parvum
por: Nguyen-Ho-Bao, Tran, et al.
Publicado: (2022)

Antifungal Activity of Linear and Disulfide-Cyclized Ultrashort Cationic Lipopeptides Alone and in Combination with Fluconazole against Vulvovaginal Candida spp.
por: Czechowicz, Paulina, et al.
Publicado: (2021)

Molecular targets for antifungals in amino acid and protein biosynthetic pathways
por: Kuplińska, Aleksandra, et al.
Publicado: (2021)

Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity
por: Ptaszyńska, Natalia, et al.
Publicado: (2020)

Xanthone synthetic derivatives with high anticandidal activity and positive mycostatic selectivity index values
por: Rząd, Kamila, et al.
Publicado: (2023)

Preclinical evaluation of novel imidazoacridinone derivatives with potent activity against experimental colorectal cancer.
por: Burger, A. M., et al.
Publicado: (1996)

Solid lipid nanoparticles modified with stearic acid–octaarginine for oral administration of insulin
por: Zhang, Zhen-Hai, et al.
Publicado: (2012)

In Vitro Efficiency of Antimicrobial Peptides against Staphylococcal Pathogens Associated with Canine Pyoderma
por: Jarosiewicz, Małgorzata, et al.
Publicado: (2020)

Effective photo-enhancement of cellular activity of fluorophore-octaarginine antisense PNA conjugates correlates with singlet oxygen formation, endosomal escape and chromophore lipophilicity
por: Yarani, Reza, et al.
Publicado: (2018)

Cellular uptake, cytotoxicity and DNA-binding studies of the novel imidazoacridinone antineoplastic agent C1311
por: Burger, A M, et al.
Publicado: (1999)

Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells
por: Niemira, Magdalena, et al.
Publicado: (2020)

Live‐cell imaging of octaarginine‐modified polymer dots via single particle tracking
por: Luo, Yao, et al.
Publicado: (2019)

The imidazoacridinone C-1311 induces p53-dependent senescence or p53-independent apoptosis and sensitizes cancer cells to radiation
por: Skwarska, Anna, et al.
Publicado: (2017)

Combined anticancer therapy with imidazoacridinone analogue C‐1305 and paclitaxel in human lung and colon cancer xenografts—Modulation of tumour angiogenesis
por: Świtalska, Marta, et al.
Publicado: (2022)

Hydrocarbon Stapled Antimicrobial Peptides
por: Migoń, Dorian, et al.
Publicado: (2018)

Comparative Study on Antistaphylococcal Activity of Lipopeptides in Various Culture Media
por: Jaśkiewicz, Maciej, et al.
Publicado: (2017)

Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers
por: Adar, Y, et al.
Publicado: (2012)

Photodynamic Inactivation of Candida albicans with Imidazoacridinones: Influence of Irradiance, Photosensitizer Uptake and Reactive Oxygen Species Generation
por: Taraszkiewicz, Aleksandra, et al.
Publicado: (2015)

Inhibitors of amino acids biosynthesis as antifungal agents
por: Jastrzębowska, Kamila, et al.
Publicado: (2014)

Rose Bengal-Mediated Photoinactivation of Multidrug Resistant Pseudomonas aeruginosa Is Enhanced in the Presence of Antimicrobial Peptides
por: Nakonieczna, Joanna, et al.
Publicado: (2018)

Citropin 1.1 Trifluoroacetate to Chloride Counter-Ion Exchange in HCl-Saturated Organic Solutions: An Alternative Approach
por: Sikora, Karol, et al.
Publicado: (2017)

Theogallin-to-Gallic-Acid Ratio as a Potential Biomarker of Pu-Erh Teas
por: Karwowska, Kaja, et al.
Publicado: (2023)

Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2
por: Migoń, Dorian, et al.
Publicado: (2018)

Octaarginine-modified gold nanoparticles enhance the radiosensitivity of human colorectal cancer cell line LS180 to megavoltage radiation
por: Zhang, Xuyang, et al.
Publicado: (2018)

Glycosaminoglycan Binding and Non-Endocytic Membrane Translocation of Cell-Permeable Octaarginine Monitored by Real-Time In-Cell NMR Spectroscopy
por: Takechi-Haraya, Yuki, et al.
Publicado: (2017)

Influence of Amphibian Antimicrobial Peptides and Short Lipopeptides on Bacterial Biofilms Formed on Contact Lenses
por: Maciejewska, Magdalena, et al.
Publicado: (2016)

Antimicrobial Activity of Selected Antimicrobial Peptides Against Planktonic Culture and Biofilm of Acinetobacter baumannii
por: Jaśkiewicz, Maciej, et al.
Publicado: (2018)

Ultrashort Cationic Lipopeptides–Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis
por: Neubauer, Damian, et al.
Publicado: (2020)

The Role of Counter-Ions in Peptides—An Overview
por: Sikora, Karol, et al.
Publicado: (2020)

Anticandidal Activity of Omiganan and Its Retro Analog Alone and in Combination with Fluconazole
por: Czechowicz, Paulina, et al.
Publicado: (2021)

Glycosylated Lipopeptides—Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity
por: Sikora, Karol, et al.
Publicado: (2023)

Interaction of Positively Charged Oligopeptides with Blood Plasma Proteins
por: Kotynia, Aleksandra, et al.
Publicado: (2023)

Retro analog concept: comparative study on physico-chemical and biological properties of selected antimicrobial peptides
por: Neubauer, Damian, et al.
Publicado: (2017)

Cell killing by the novel imidazoacridinone antineoplastic agent, C-1311, is inhibited at high concentrations coincident with dose-differentiated cell cycle perturbation.
por: Lamb, J., et al.
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_sh0ekkm54h8t6kvpkto2gndine