Cargando…

Nanostructured Lipid Carriers Can Enhance Oral Absorption of Khellin, a Natural Pleiotropic Molecule

A novel formulation based on nanostructured lipid carriers (NLCs) was developed to increase solubility and intestinal absorption of khellin. K-NLCs were prepared with stearic acid, hempseed oil, Brij S20, and Labrafil M 1944 CS, using the emulsification-ultrasonication method. Developed nanoparticle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vanti, Giulia, Muti, Lucrezia, D’Ambrosio, Mario, Grifoni, Lucia, Bergonzi, Maria Camilla, Luceri, Cristina, Bilia, Anna Rita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705784/ https://www.ncbi.nlm.nih.gov/pubmed/34946734 http://dx.doi.org/10.3390/molecules26247657

Ejemplares similares

The Anti-Arthritic Efficacy of Khellin Loaded in Ascorbyl Decanoate Nanovesicles after an Intra-Articular Administration
por: Vanti, Giulia, et al.
Publicado: (2021)

Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin
por: Piazzini, Vieri, et al.
Publicado: (2019)

Development and Percutaneous Permeation Study of Escinosomes, Escin-Based Nanovesicles Loaded with Berberine Chloride
por: Vanti, Giulia, et al.
Publicado: (2019)

Formulation of a Phenol-Rich Extract from Unripe Olives (Olea europaea L.) in Microemulsion to Improve Its Solubility and Intestinal Permeability
por: Cecchi, Lorenzo, et al.
Publicado: (2020)

Co-Delivery of Berberine Chloride and Tariquidar in Nanoliposomes Enhanced Intracellular Berberine Chloride in a Doxorubicin-Resistant K562 Cell Line Due to P-gp Overexpression
por: Vanti, Giulia, et al.
Publicado: (2021)

Khellin in the Treatment of Angina Pectoris
por: Hill, R., et al.
Publicado: (1953)

Evaluation and Comparison of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) as Vectors to Develop Hydrochlorothiazide Effective and Safe Pediatric Oral Liquid Formulations
por: Mura, Paola, et al.
Publicado: (2021)

Promising Nanocarriers to Enhance Solubility and Bioavailability of Cannabidiol for a Plethora of Therapeutic Opportunities
por: Grifoni, Lucia, et al.
Publicado: (2022)

Nanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches
por: Piazzini, Vieri, et al.
Publicado: (2017)

Development of Gel-in-Oil Emulsions for Khellin Topical Delivery
por: Pereira, Joana, et al.
Publicado: (2020)

Escinosomes: Safe and Successful Nanovesicles to Deliver Andrographolide by a Subcutaneous Route in a Mice Model of Oxaliplatin-Induced Neuropathy
por: Vanti, Giulia, et al.
Publicado: (2022)

Glycerosome of Melissa officinalis L. Essential Oil for Effective Anti-HSV Type 1
por: Vanti, Giulia, et al.
Publicado: (2020)

Halloysite Nanotubes Coated by Chitosan for the Controlled Release of Khellin
por: Lisuzzo, Lorenzo, et al.
Publicado: (2020)

Emergent Strategies for Natural Products Delivery
por: Bilia, Anna Rita, et al.
Publicado: (2020)

Synthesis of New Visnagen and Khellin Furochromone Pyrimidine Derivatives and Their Anti-Inflammatory and Analgesic Activity
por: Abu-Hashem, Ameen Ali, et al.
Publicado: (2011)

Microemulsions Enhance the In Vitro Antioxidant Activity of Oleanolic Acid in RAW 264.7 Cells
por: De Stefani, Chiara, et al.
Publicado: (2022)

Effect of cell-penetrating peptide-coated nanostructured lipid carriers on the oral absorption of tripterine
por: Chen, Yan, et al.
Publicado: (2012)

Essential Oil of Artemisia annua L.: An Extraordinary Component with Numerous Antimicrobial Properties
por: Bilia, Anna Rita, et al.
Publicado: (2014)

Enhanced Neuroprotective Effects of Panax ginseng G115(®) and Ginkgo biloba GK501(®) Combinations In Vitro Models of Excitotoxicity
por: Landucci, Elisa, et al.
Publicado: (2019)

Stealth and Cationic Nanoliposomes as Drug Delivery Systems to Increase Andrographolide BBB Permeability
por: Piazzini, Vieri, et al.
Publicado: (2018)

Pentacyclic Triterpenes from Olive Leaves Formulated in Microemulsion: Characterization and Role in De Novo Lipogenesis in HepG2 Cells
por: Vasarri, Marzia, et al.
Publicado: (2023)

Combination of Nanodelivery Systems and Constituents Derived from Novel Foods: A Comprehensive Review
por: Truzzi, Eleonora, et al.
Publicado: (2023)

Essential Oils Loaded in Nanosystems: A Developing Strategy for a Successful Therapeutic Approach
por: Bilia, Anna Rita, et al.
Publicado: (2014)

Stable, Monodisperse, and Highly Cell-Permeating Nanocochleates from Natural Soy Lecithin Liposomes
por: Asprea, Martina, et al.
Publicado: (2019)

Improving intestinal absorption and oral bioavailability of curcumin via taurocholic acid-modified nanostructured lipid carriers
por: Tian, Cihui, et al.
Publicado: (2017)

EGCG intestinal absorption and oral bioavailability enhancement using folic acid-functionalized nanostructured lipid carriers
por: Granja, Andreia, et al.
Publicado: (2019)

Nanovesicles Loaded with Origanum onites and Satureja thymbra Essential Oils and Their Activity against Food-Borne Pathogens and Spoilage Microorganisms
por: Vanti, Giulia, et al.
Publicado: (2021)

Khellin and Visnagin Differentially Modulate AHR Signaling and Downstream CYP1A Activity in Human Liver Cells
por: Vrzal, Radim, et al.
Publicado: (2013)

The G115 standardized ginseng extract: an example for safety, efficacy, and quality of an herbal medicine
por: Bilia, Anna R., et al.
Publicado: (2020)

Antineoplastics Encapsulated in Nanostructured Lipid Carriers
por: Rodrigues da Silva, Gustavo Henrique, et al.
Publicado: (2021)

Successful Brain Delivery of Andrographolide Loaded in Human Albumin Nanoparticles to TgCRND8 Mice, an Alzheimer’s Disease Mouse Model
por: Bilia, Anna Rita, et al.
Publicado: (2019)

Antinociceptive Action of Thymoquinone-Loaded Liposomes in an In Vivo Model of Tendinopathy
por: Micheli, Laura, et al.
Publicado: (2023)

Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis
por: Micheli, Laura, et al.
Publicado: (2019)

Nanostructured Lipid Carriers: A potential drug carrier for cancer chemotherapy
por: Selvamuthukumar, Subramanian, et al.
Publicado: (2012)

Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule
por: Lee, Sang Gon, et al.
Publicado: (2013)

Enhancing the Oral Bioavailability of Candesartan Cilexetil Loaded Nanostructured Lipid Carriers: In Vitro Characterization and Absorption in Rats after Oral Administration
por: Anwar, Walid, et al.
Publicado: (2020)

Preparation of Liposomal Formulations for Ocular Delivery of Thymoquinone: In Vitro Evaluation in HCEC-2 e HConEC Cells
por: Landucci, Elisa, et al.
Publicado: (2021)

Solubility and Permeability Enhancement of Oleanolic Acid by Solid Dispersion in Poloxamers and γ-CD
por: De Stefani, Chiara, et al.
Publicado: (2022)

Development and validation of high-performance liquid chromatography and high-performance thin-layer chromatography methods for the quantification of khellin in Ammi visnaga seed
por: Kamal, Abid, et al.
Publicado: (2015)

Successful Treatment of Refractory Vitiligo with a Combination of Khellin and 308-nm Excimer Lamp: An Open-Label, 1-Year Prospective Study
por: Fenniche, Samy, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ftanoof1le1gj1kjtkk3qbaf22