Cargando…

Quantification of Type I Interferon Inhibition by Viral Proteins: Ebola Virus as a Case Study

Type I interferons (IFNs) are cytokines with both antiviral properties and protective roles in innate immune responses to viral infection. They induce an antiviral cellular state and link innate and adaptive immune responses. Yet, viruses have evolved different strategies to inhibit such host respon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Locke, Macauley, Lythe, Grant, López-García, Martín, Muñoz-Fontela, César, Carroll, Miles, Molina-París, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705787/ https://www.ncbi.nlm.nih.gov/pubmed/34960709 http://dx.doi.org/10.3390/v13122441

Ejemplares similares

Quantification of Ebola virus replication kinetics in vitro
por: Liao, Laura E., et al.
Publicado: (2020)

Fusion and fission events regulate endosome maturation and viral escape
por: Castro, Mario, et al.
Publicado: (2021)

Role of Type I Interferons on Filovirus Pathogenesis
por: Escudero-Pérez, Beatriz, et al.
Publicado: (2019)

Ebola Virus Disease in Humans: Pathophysiology and Immunity
por: Muñoz-Fontela, César, et al.
Publicado: (2017)

First passage events in biological systems with non-exponential inter-event times
por: Castro, Mario, et al.
Publicado: (2018)

Counting generations in birth and death processes with competing Erlang and exponential waiting times
por: Belluccini, Giulia, et al.
Publicado: (2022)

Mathematical Model of Naive T Cell Division and Survival IL-7 Thresholds
por: Reynolds, Joseph, et al.
Publicado: (2013)

Mathematics in modern immunology
por: Castro, Mario, et al.
Publicado: (2016)

Interferon-γ Inhibits Ebola Virus Infection
por: Rhein, Bethany A., et al.
Publicado: (2015)

A stochastic T cell response criterion
por: Currie, James, et al.
Publicado: (2012)

How many TCR clonotypes does a body maintain?
por: Lythe, Grant, et al.
Publicado: (2016)

Modeling early events in Francisella tularensis pathogenesis
por: Gillard, Joseph J., et al.
Publicado: (2014)

Why are cell populations maintained via multiple compartments?
por: Feliciangeli, Flavia, et al.
Publicado: (2022)

Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition
por: Di Palma, Francesco, et al.
Publicado: (2019)

A Novel Stochastic Multi-Scale Model of Francisella tularensis Infection to Predict Risk of Infection in a Laboratory
por: Carruthers, Jonathan, et al.
Publicado: (2018)

Fate of a Naive T Cell: A Stochastic Journey
por: de la Higuera, Luis, et al.
Publicado: (2019)

Interferon-Induced HERC5 Inhibits Ebola Virus Particle Production and Is Antagonized by Ebola Glycoprotein
por: Paparisto, Ermela, et al.
Publicado: (2021)

Regulation of Ebola virus VP40 matrix protein by SUMO
por: Baz-Martínez, Maite, et al.
Publicado: (2016)

Stochastic dynamics of Francisella tularensis infection and replication
por: Carruthers, Jonathan, et al.
Publicado: (2020)

Quantifying T Cell Cross-Reactivity: Influenza and Coronaviruses
por: Gaevert, Jessica Ann, et al.
Publicado: (2021)

Receptor Pre-Clustering and T cell Responses: Insights into Molecular Mechanisms
por: Castro, Mario, et al.
Publicado: (2014)

Variation around the dominant viral genome sequence contributes to viral load and outcome in patients with Ebola virus disease
por: Dong, Xiaofeng, et al.
Publicado: (2020)

Interferon and Ocular Viral Disease
por: Galin, Miles A., et al.
Publicado: (1970)

Human Diversity of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen Class I Alleles and Ebola Virus Disease Outcomes
por: Wawina-Bokalanga, Tony, et al.
Publicado: (2021)

Avatar Mice Underscore the Role of the T Cell-Dendritic Cell Crosstalk in Ebola Virus Disease and Reveal Mechanisms of Protection in Survivors
por: Rottstegge, Monika, et al.
Publicado: (2022)

A Stochastic Intracellular Model of Anthrax Infection With Spore Germination Heterogeneity
por: Williams, Bevelynn, et al.
Publicado: (2021)

An Investigation of the Effect of Transfected Defective, Ebola Virus Genomes on Ebola Replication
por: Smither, Sophie J., et al.
Publicado: (2020)

From pre-DP, post-DP, SP4, and SP8 Thymocyte Cell Counts to a Dynamical Model of Cortical and Medullary Selection
por: Sawicka, Maria, et al.
Publicado: (2014)

The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses
por: Lubaki, Ndongala Michel, et al.
Publicado: (2016)

Designs and Characterization of Subunit Ebola GP Vaccine Candidates: Implications for Immunogenicity
por: Agnolon, Valentina, et al.
Publicado: (2020)

Ebola Virus Disease Survivors Show More Efficient Antibody Immunity than Vaccinees Despite Similar Levels of Circulating Immunoglobulins
por: Koch, Till, et al.
Publicado: (2020)

Kinetics of Soluble Mediators of the Host Response in Ebola Virus Disease
por: Kerber, Romy, et al.
Publicado: (2018)

Comparative pathogenesis of Ebola virus and Reston virus infection in humanized mice
por: Escudero-Pérez, Beatriz, et al.
Publicado: (2019)

Ebola viral disease and pregnancy
por: Black, Benjamin O, et al.
Publicado: (2015)

Quorum-Sensing in CD4(+) T Cell Homeostasis: A Hypothesis and a Model
por: Almeida, Afonso R. M., et al.
Publicado: (2012)

Against Ebola: type I interferon guard risk and mesenchymal stromal cell combat sepsis
por: Zhang, Lei, et al.
Publicado: (2015)

Quantifying the phosphorylation timescales of receptor–ligand complexes: a Markovian matrix-analytic approach
por: López-García, M., et al.
Publicado: (2018)

Transcriptional role of p53 in interferon-mediated antiviral immunity
por: Muñoz-Fontela, César, et al.
Publicado: (2008)

Curcumin and Natural Derivatives Inhibit Ebola Viral Proteins: An In silico Approach
por: Baikerikar, Shruti
Publicado: (2017)

Repurposing of berbamine hydrochloride to inhibit Ebola virus by targeting viral glycoprotein
por: Yi, Dongrong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_curj69panc8mv5tln21gju0frt