Cargando…

YPK9 and WHI2 Negatively Interact during Oxidative Stress

Yeast PARK9 (YPK9) shares homology with human ATP13A2, which encodes a polyamine transporter implicated in juvenile forms of Parkinson’s disease. We used YPK9 to gain insight into how ATP13A2 affects cell growth and sensitivity to oxidative stress. Surprisingly, the YPK9 deletion strain from the Sac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Joseph, Florenal, Miller, Darach, Evgrafov, Oleg V., Chirico, William J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705791/ https://www.ncbi.nlm.nih.gov/pubmed/34946185 http://dx.doi.org/10.3390/microorganisms9122584

Ejemplares similares

Interaction of Cu(II) and Ni(II) with Ypk9 Protein Fragment via NMR Studies
por: Peana, Massimiliano Francesco, et al.
Publicado: (2014)

The conserved Pkh–Ypk kinase cascade is required for endocytosis in yeast
por: deHart, Amy K.A., et al.
Publicado: (2002)

Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9
por: Plank, Michael, et al.
Publicado: (2020)

Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress
por: Muir, Alexander, et al.
Publicado: (2015)

The AGC Kinase YpkA Regulates Sphingolipids Biosynthesis and Physically Interacts With SakA MAP Kinase in Aspergillus fumigatus
por: Fabri, João Henrique Tadini Marilhano, et al.
Publicado: (2019)

Functional Characterization of Aspergillus nidulans ypkA, a Homologue of the Mammalian Kinase SGK
por: Colabardini, Ana Cristina, et al.
Publicado: (2013)

The Ypk1 protein kinase signaling pathway is rewired and not essential for viability in Candida albicans
por: Ramírez-Zavala, Bernardo, et al.
Publicado: (2023)

Direct and negative regulation of the sycO-ypkA-ypoJ operon by cyclic AMP receptor protein (CRP) in Yersinia pestis
por: Zhan, Lingjun, et al.
Publicado: (2009)

The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites
por: Leskoske, Kristin L., et al.
Publicado: (2017)

TOR complex 2–Ypk1 signaling regulates actin polarization via reactive oxygen species
por: Niles, Brad J., et al.
Publicado: (2014)

TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids
por: Muir, Alexander, et al.
Publicado: (2014)

TORC1 Promotes Phosphorylation of Ribosomal Protein S6 via the AGC Kinase Ypk3 in Saccharomyces cerevisiae
por: González, Asier, et al.
Publicado: (2015)

Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways
por: Sun, Yidi, et al.
Publicado: (2012)

Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy
por: Vlahakis, Ariadne, et al.
Publicado: (2017)

Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death
por: Rego, António, et al.
Publicado: (2020)

Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae
por: Niles, Brad J., et al.
Publicado: (2012)

Aft1 Nuclear Localization and Transcriptional Response to Iron Starvation Rely upon TORC2/Ypk1 Signaling and Sphingolipid Biosynthesis
por: Montellà-Manuel, Sandra, et al.
Publicado: (2023)

Editorial: Olfactory neuroepithelium-derived cellular models to study neurological and psychiatric disorders
por: Yang, Kun, et al.
Publicado: (2023)

Why genes overlap in viruses
por: Chirico, Nicola, et al.
Publicado: (2010)

Phosphorylation of mRNA-Binding Proteins Puf1 and Puf2 by TORC2-Activated Protein Kinase Ypk1 Alleviates Their Repressive Effects
por: Galez, Henri A., et al.
Publicado: (2021)

13 reasons why the brain is susceptible to oxidative stress
por: Cobley, James Nathan, et al.
Publicado: (2018)

The Conserved SKN-1/Nrf2 Stress Response Pathway Regulates Synaptic Function in Caenorhabditis elegans
por: Staab, Trisha A., et al.
Publicado: (2013)

Developmental Origins of Kidney Disease: Why Oxidative Stress Matters?
por: Hsu, Chien-Ning, et al.
Publicado: (2020)

TOR complex 2–regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain–containing proteins located at plasma membrane–endoplasmic reticulum contact sites
por: Roelants, Françoise M., et al.
Publicado: (2018)

Biological mechanism of cell oxidative stress and death during short-term exposure to nano CuO
por: Moschini, Elisa, et al.
Publicado: (2023)

Why Teams Win: 9 Keys to Success in Business, Sport and Beyond
por: Miller, Dr Saul L
Publicado: (2009)

Systematic identification of factors mediating accelerated mRNA degradation in response to changes in environmental nitrogen
por: Miller, Darach, et al.
Publicado: (2018)

Oxidative Stress in Alzheimer's Disease: Why Did Antioxidant Therapy Fail?
por: Persson, Torbjörn, et al.
Publicado: (2014)

How and Why Chromosomes Interact with the Cytoskeleton during Meiosis
por: Kim, Hyung Jun, et al.
Publicado: (2022)

Why Do Ferroelectrics Exhibit Negative Capacitance?
por: Hoffmann, Michael, et al.
Publicado: (2019)

Why was GOG-0213 a negative trial?
por: Ehmann, Sarah, et al.
Publicado: (2020)

Why a Scialog on negative emissions science?
por: Michelson, Evan S., et al.
Publicado: (2021)

Conference Modern Engineering : Science and Education
por: Evgrafov, Alexander
Publicado: (2017)

Conference “Modern Engineering : Science and Education”
por: Evgrafov, Alexander
Publicado: (2015)

Modern Engineering : Science and Education
por: Evgrafov, Alexander
Publicado: (2016)

TORC2-Dependent Ypk1-Mediated Phosphorylation of Lam2/Ltc4 Disrupts Its Association with the β-Propeller Protein Laf1 at Endoplasmic Reticulum-Plasma Membrane Contact Sites in the Yeast Saccharomyces cerevisiae
por: Topolska, Magdalena, et al.
Publicado: (2020)

Stress perfusion cardiac MRI in women
por: h-Ici, Darach O, et al.
Publicado: (2011)

Asymptotic estimates and entire functions
por: Evgrafov, M A
Publicado: (1961)

Complete mitochondrial genome sequences of five rockfishes (Perciformes: Sebastes)
por: Sandel, Michael W., et al.
Publicado: (2018)

Why (and how) we should publish negative data
por: Nimpf, Simon, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_man17sov6dssbs8ncrulbrh36r