The Toxic Mechanism of Gliotoxins and Biosynthetic Strategies for Toxicity Prevention

Gliotoxin is a kind of epipolythiodioxopiperazine derived from different fungi that is characterized by a disulfide bridge. Gliotoxins can be biosynthesized by a gli gene cluster and regulated by a positive GliZ regulator. Gliotoxins show cytotoxic effects via the suppression the function of macroph...

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Detalles Bibliográficos
Autores principales: Ye, Wei, Liu, Taomei, Zhang, Weiyang, Zhang, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705807/
https://www.ncbi.nlm.nih.gov/pubmed/34948306
http://dx.doi.org/10.3390/ijms222413510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705807/
https://www.ncbi.nlm.nih.gov/pubmed/34948306
http://dx.doi.org/10.3390/ijms222413510

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