Modulation of Epithelial Mesenchymal Transition after AGTR-1 Gene Edition by Crispr/Cas9 and Losartan Treatment in Mammary Tumor Cell Line: A Comparative Study between Human and Canine Species

Breast cancer is the most prevalent tumor type among women and female dogs. Tumor malignancy is characterized by the epithelial-to-mesenchymal transition (EMT) which leads to the metastasis formation. The inhibition of angiotensin II type I receptor (AGTR1) by an antagonist such as losartan can supp...

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Detalles Bibliográficos
Autores principales: Moschetta-Pinheiro, Marina Gobbe, Colombo, Jucimara, de Godoy, Bianca Lara Venâncio, Balan, Julia Ferreira, Nascimento, Bianca Carlos, Zuccari, Debora Aparecida Pires de Campos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705831/
https://www.ncbi.nlm.nih.gov/pubmed/34947958
http://dx.doi.org/10.3390/life11121427

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