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The Processivity of Telomerase: Insights from Kinetic Simulations and Analyses
Telomerases are moderately processive reverse transcriptases that use an integral RNA template to extend the 3′ end of linear chromosomes. Processivity values, defined as the probability of extension rather than dissociation, range from about 0.7 to 0.99 at each step. Consequently, an average of ten...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705835/ https://www.ncbi.nlm.nih.gov/pubmed/34946615 http://dx.doi.org/10.3390/molecules26247532 |