Sulfonated Amphiphilic Poly(α)glutamate Amine—A Potential siRNA Nanocarrier for the Treatment of Both Chemo-Sensitive and Chemo-Resistant Glioblastoma Tumors

Development of chemo-resistance is a major challenge in glioblastoma (GB) treatment. This phenomenon is often driven by increased activation of genes associated with DNA repair, such as the alkyl-removing enzyme O(6)-methylguanine-DNA methyltransferase (MGMT) in combination with overexpression of ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Krivitsky, Adva, Pozzi, Sabina, Yeini, Eilam, Israeli Dangoor, Sahar, Zur, Tal, Golan, Sapir, Krivitsky, Vadim, Albeck, Nitzan, Pisarevsky, Evgeny, Ofek, Paula, Madi, Asaf, Satchi-Fainaro, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705840/
https://www.ncbi.nlm.nih.gov/pubmed/34959480
http://dx.doi.org/10.3390/pharmaceutics13122199

Ejemplares similares

Ejemplares similares