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Development and In Vitro/In Vivo Evaluation of pH-Sensitive Polymeric Nanoparticles Loaded Hydrogel for the Management of Psoriasis

Methotrexate (MTX), the gold standard against psoriasis, poses severe problems when administered systemically viz increased toxicity, poor solubility and adverse reactions. Hence, a topical formulation of MTX for the management of psoriasis can be an effective approach. The present study aimed to de...

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Detalles Bibliográficos
Autores principales: Asad, Muhammad Imran, Khan, Dildar, Rehman, Asim ur, Elaissari, Abdelhamid, Ahmed, Naveed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705938/
https://www.ncbi.nlm.nih.gov/pubmed/34947782
http://dx.doi.org/10.3390/nano11123433