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Protection of Cholinergic Neurons against Zinc Toxicity by Glial Cells in Thiamine-Deficient Media

Brain pathologies evoked by thiamine deficiency can be aggravated by mild zinc excess. Cholinergic neurons are the most susceptible to such cytotoxic signals. Sub-toxic zinc excess aggravates the injury of neuronal SN56 cholinergic cells under mild thiamine deficiency. The excessive cell loss is cau...

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Detalles Bibliográficos
Autores principales: Gul-Hinc, Sylwia, Michno, Anna, Zyśk, Marlena, Szutowicz, Andrzej, Jankowska-Kulawy, Agnieszka, Ronowska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705960/
https://www.ncbi.nlm.nih.gov/pubmed/34948135
http://dx.doi.org/10.3390/ijms222413337