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On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties
Optical properties of the cornea are responsible for correct vision; the ultrastructure allows optical transparency, and the biomechanical properties govern the shape, elasticity, or stiffness of the cornea, affecting ocular integrity and intraocular pressure. Therefore, the optical aberrations, cor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706034/ https://www.ncbi.nlm.nih.gov/pubmed/34940747 http://dx.doi.org/10.3390/jimaging7120280 |
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author | Ávila, Francisco J. Marcellán, Maria Concepción Remón, Laura |
author_facet | Ávila, Francisco J. Marcellán, Maria Concepción Remón, Laura |
author_sort | Ávila, Francisco J. |
collection | PubMed |
description | Optical properties of the cornea are responsible for correct vision; the ultrastructure allows optical transparency, and the biomechanical properties govern the shape, elasticity, or stiffness of the cornea, affecting ocular integrity and intraocular pressure. Therefore, the optical aberrations, corneal transparency, structure, and biomechanics play a fundamental role in the optical quality of human vision, ocular health, and refractive surgery outcomes. However, the inter-relationships of those properties are not yet reported at a macroscopic scale within the hierarchical structure of the cornea. This work explores the relationships between the biomechanics, structure, and optical properties (corneal aberrations and optical density) at a macro-structural level of the cornea through dual Placido–Scheimpflug imaging and air-puff tonometry systems in a healthy young adult population. Results showed correlation between optical transparency, corneal macrostructure, and biomechanics, whereas corneal aberrations and in particular spherical terms remained independent. A compensation mechanism for the spherical aberration is proposed through corneal shape and biomechanics. |
format | Online Article Text |
id | pubmed-8706034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87060342021-12-25 On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties Ávila, Francisco J. Marcellán, Maria Concepción Remón, Laura J Imaging Article Optical properties of the cornea are responsible for correct vision; the ultrastructure allows optical transparency, and the biomechanical properties govern the shape, elasticity, or stiffness of the cornea, affecting ocular integrity and intraocular pressure. Therefore, the optical aberrations, corneal transparency, structure, and biomechanics play a fundamental role in the optical quality of human vision, ocular health, and refractive surgery outcomes. However, the inter-relationships of those properties are not yet reported at a macroscopic scale within the hierarchical structure of the cornea. This work explores the relationships between the biomechanics, structure, and optical properties (corneal aberrations and optical density) at a macro-structural level of the cornea through dual Placido–Scheimpflug imaging and air-puff tonometry systems in a healthy young adult population. Results showed correlation between optical transparency, corneal macrostructure, and biomechanics, whereas corneal aberrations and in particular spherical terms remained independent. A compensation mechanism for the spherical aberration is proposed through corneal shape and biomechanics. MDPI 2021-12-18 /pmc/articles/PMC8706034/ /pubmed/34940747 http://dx.doi.org/10.3390/jimaging7120280 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ávila, Francisco J. Marcellán, Maria Concepción Remón, Laura On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties |
title | On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties |
title_full | On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties |
title_fullStr | On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties |
title_full_unstemmed | On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties |
title_short | On the Relationship between Corneal Biomechanics, Macrostructure, and Optical Properties |
title_sort | on the relationship between corneal biomechanics, macrostructure, and optical properties |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706034/ https://www.ncbi.nlm.nih.gov/pubmed/34940747 http://dx.doi.org/10.3390/jimaging7120280 |
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